C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activating transcription factor 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000396680 ATF4-201 ENSG00000128272 9606 + 22:39520564-39522685 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000396680
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000396680 86.491±0.00 102.664±0.00 9.744±0.00 52.323±13.91 58.944±31.42 154.410±133.26 34.351±28.20 57.562±20.07 50.131±11.99 87.337±66.08 117.287±41.67 87.791±51.53 125.996±42.01 68.293±30.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003MS CIL_0003MS_0001 CGP 22:39499432-39522685
CIL_0005W7 CIL_0005W7_0001 CGP 22:39519695-39532855

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000981 IC sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001046 ISS core promoter sequence-specific DNA binding
GO:0003677 ISS DNA binding
GO:0003700 ISS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006094 ISS gluconeogenesis
GO:0006355 ISS:IEA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0006520 TAS cellular amino acid metabolic process
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0032922 ISS circadian regulation of gene expression
GO:0034399 IDA nuclear periphery
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0036091 IMP positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043005 IDA neuron projection
GO:0043065 TAS positive regulation of apoptotic process
GO:0043525 ISS positive regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044267 TAS cellular protein metabolic process
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0070059 ISS intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1903204 IGI negative regulation of oxidative stress-induced neuron death
GO:1990037 IDA Lewy body core
GO:1990440 IMP positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000109605 Atf4-201 protein_coding Mus_musculus 0 1493

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