C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: estrogen receptor 2 (beta)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000110421 Esr2-001 ENSMUSG00000021055 10090 - 12:76120419-76167715 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000110421
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000110421 0.056±0.03 0.054±0.00 0.020±0.00 0.034±0.02 0.248±0.09 0.031±0.01 0.103±0.05 0.015±0.01 0.403±0.09 0.057±0.01 11.634±4.99 0.029±0.03 0.055±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00010O CIL_00010O_0002 CGP 12:75818134-76177259

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001541 IMP ovarian follicle development
GO:0001764 IMP neuron migration
GO:0003677 IDA DNA binding
GO:0005496 ISS steroid binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007420 IMP brain development
GO:0008270 IEA zinc ion binding
GO:0008285 IGI negative regulation of cell proliferation
GO:0008628 IMP hormone-mediated apoptotic signaling pathway
GO:0030284 IEA estrogen receptor activity
GO:0030520 IMP intracellular estrogen receptor signaling pathway
GO:0042127 IMP regulation of cell proliferation
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0051091 ISS positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060065 IGI uterus development
GO:0060068 IGI vagina development
GO:0060740 IMP prostate gland epithelium morphogenesis
GO:0060743 IMP epithelial cell maturation involved in prostate gland development
GO:0060766 IMP negative regulation of androgen receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000267525 ESR2-201 protein_coding Homo_sapiens 0 933
ENST00000341099 ESR2-001 protein_coding Homo_sapiens 0 1637
ENST00000344288 ESR2-008 nonsense_mediated_decay Homo_sapiens 0 933
ENST00000353772 ESR2-202 protein_coding Homo_sapiens 0 1397
ENST00000358599 ESR2-002 protein_coding Homo_sapiens 0 1397
ENST00000553796 ESR2-011 protein_coding Homo_sapiens 0 1367
ENST00000554520 ESR2-006 processed_transcript Homo_sapiens 0 760
ENST00000554572 ESR2-003 protein_coding Homo_sapiens 0 1397
ENST00000555278 ESR2-012 protein_coding Homo_sapiens 0 1367
ENST00000555483 ESR2-007 processed_transcript Homo_sapiens 0 710
ENST00000555783 ESR2-009 processed_transcript Homo_sapiens 0 274
ENST00000556275 ESR2-004 protein_coding Homo_sapiens 0 1397
ENST00000557772 ESR2-005 protein_coding Homo_sapiens 0 1367

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