C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2 alpha kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000110870 Eif2ak4-004 ENSMUSG00000005102 10090 + 2:118412346-118475234 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonHeartTestisENSMUST00000110870
Transcript ID Brain Colon Heart Testis
ENSMUST00000110870 1.334±0.10 0.800±0.00 0.278±0.00 0.329±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W0 CIL_0008W0_0002 VISTA 2:118232227-118834856
CIL_0006QT CIL_0006QT_0002 CGP 2:118277110-118475234
CIL_0006QZ CIL_0006QZ_0002 CGP 2:118388618-118479711

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004694 IDA eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 IEA ATP binding
GO:0006446 ISS regulation of translational initiation
GO:0006468 IDA protein phosphorylation
GO:0009267 IDA cellular response to starvation
GO:0017148 IGI negative regulation of translation
GO:0022626 ISS cytosolic ribosome
GO:0030968 IMP endoplasmic reticulum unfolded protein response
GO:0042803 IEA protein homodimerization activity
GO:0043558 IDA regulation of translational initiation in response to stress

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263791 EIF2AK4-001 protein_coding Homo_sapiens 0 4868
ENST00000558557 EIF2AK4-005 retained_intron Homo_sapiens 0 1267
ENST00000558629 EIF2AK4-004 retained_intron Homo_sapiens 0 2800
ENST00000558743 EIF2AK4-007 retained_intron Homo_sapiens 0 291
ENST00000558823 EIF2AK4-009 protein_coding Homo_sapiens 0 329
ENST00000559311 EIF2AK4-006 processed_transcript Homo_sapiens 0 529
ENST00000559624 EIF2AK4-002 protein_coding Homo_sapiens 0 1219
ENST00000560855 EIF2AK4-003 protein_coding Homo_sapiens 0 3131

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