C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: non-catalytic region of tyrosine kinase adaptor protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112874 Nck1-002 ENSMUSG00000032475 10090 - 9:100495003-100506856 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000112874
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000112874 6.386±1.12 9.229±4.01 6.454±1.79 4.281±1.06 1.645±0.88 4.977±0.91 2.420±0.45 4.461±3.19 5.264±1.56 6.098±1.72 8.927±8.30 14.323±2.96 5.085±1.49

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00092I CIL_00092I_0002 VISTA 9:99894020-100495329
CIL_0009A5 CIL_0009A5_0002 VISTA 9:99910151-100511937
CIL_0009A4 CIL_0009A4_0002 VISTA 9:99971528-100572973
CIL_0001BW CIL_0001BW_0003 CGP 9:100492293-100571090

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005911 IDA cell-cell junction
GO:0006930 IGI substrate-dependent cell migration, cell extension
GO:0007015 IMP actin filament organization
GO:0012506 IDA vesicle membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016477 IMP cell migration
GO:0019887 IEA protein kinase regulator activity
GO:0019904 IPI protein domain specific binding
GO:0030032 IMP lamellipodium assembly
GO:0030838 IGI positive regulation of actin filament polymerization
GO:0045859 IEA regulation of protein kinase activity
GO:0051707 IMP response to other organism

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000109339 nck1b-201 protein_coding Danio_rerio 3.9937e-43 180
ENSDART00000132648 nck1b-001 protein_coding Danio_rerio 3.9937e-43 180
ENST00000288986 NCK1-001 protein_coding Homo_sapiens 0 1604
ENST00000467911 NCK1-011 protein_coding Homo_sapiens 0 505
ENST00000469404 NCK1-002 protein_coding Homo_sapiens 0 1755
ENST00000481752 NCK1-003 protein_coding Homo_sapiens 0 1604
ENST00000482071 NCK1-012 retained_intron Homo_sapiens 0 817
ENST00000488930 NCK1-009 protein_coding Homo_sapiens 0 243
ENST00000491539 NCK1-004 protein_coding Homo_sapiens 0 231
ENST00000496489 NCK1-010 protein_coding Homo_sapiens 0 243

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