C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NCK adaptor protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000481752 NCK1-003 ENSG00000158092 9606 + 3:136862208-136949126 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastLungOvaryPlacentaTestisENST00000481752
Transcript ID Bladder Brain Breast Lung Ovary Placenta Testis
ENST00000481752 0.699±0.00 2.218±0.00 7.013±0.00 4.342±0.00 2.372±0.10 1.681±0.74 2.616±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004860 IDA protein kinase inhibitor activity
GO:0005102 IPI receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 NAS cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005911 IEA cell-cell junction
GO:0006417 IEA regulation of translation
GO:0006469 IDA negative regulation of protein kinase activity
GO:0006930 IEA substrate-dependent cell migration, cell extension
GO:0007015 IEA actin filament organization
GO:0007172 NAS signal complex assembly
GO:0007411 TAS axon guidance
GO:0008093 NAS cytoskeletal adaptor activity
GO:0012506 IEA vesicle membrane
GO:0016477 IEA cell migration
GO:0019887 IEA protein kinase regulator activity
GO:0019904 IEA protein domain specific binding
GO:0030032 IEA lamellipodium assembly
GO:0030159 NAS receptor signaling complex scaffold activity
GO:0030838 IMP positive regulation of actin filament polymerization
GO:0030971 IPI receptor tyrosine kinase binding
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042110 IMP T cell activation
GO:0045087 TAS innate immune response
GO:0045859 IEA regulation of protein kinase activity
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050852 TAS T cell receptor signaling pathway
GO:0051707 IEA response to other organism
GO:0060548 IDA negative regulation of cell death

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000116522 Nck1-001 protein_coding Mus_musculus 0 2143
ENSMUST00000112874 Nck1-002 protein_coding Mus_musculus 0 1604
ENSMUST00000186591 Nck1-006 protein_coding Mus_musculus 0 917
ENSMUST00000188670 Nck1-003 protein_coding Mus_musculus 0 584
ENSMUST00000122350 Gm13852-001 processed_pseudogene Mus_musculus 0 287

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