C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tuberous sclerosis 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000113867 Tsc1-007 ENSMUSG00000026812 10090 + 2:28641243-28691167 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000113867
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000113867 1.716±0.34 1.259±0.10 5.028±0.06 2.301±0.62 1.159±0.30 1.515±0.75 1.607±0.49 1.077±0.40 1.347±0.15 4.197±0.78 2.432±1.20 1.913±0.99 1.024±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000H4 CIL_0000H4_0002 CGP 2:28609450-28691167
CIL_0002XC CIL_0002XC_0002 CGP 2:28641228-28699727

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0001843 IMP neural tube closure
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0006813 IGI potassium ion transport
GO:0007399 IMP nervous system development
GO:0008285 IMP negative regulation of cell proliferation
GO:0021766 IMP hippocampus development
GO:0021987 IMP cerebral cortex development
GO:0030030 IMP cell projection organization
GO:0030695 IBA GTPase regulator activity
GO:0032007 IBA negative regulation of TOR signaling
GO:0032318 IBA regulation of Ras GTPase activity
GO:0032956 IBA regulation of actin cytoskeleton organization
GO:0033596 IBA TSC1-TSC2 complex
GO:0042552 IMP myelination
GO:0045792 IGI negative regulation of cell size
GO:0045859 IGI regulation of protein kinase activity
GO:0046323 IMP glucose import
GO:0046627 IBA negative regulation of insulin receptor signaling pathway
GO:0047485 IPI protein N-terminus binding
GO:0050808 IMP synapse organization
GO:0051726 IBA regulation of cell cycle
GO:0055007 IMP cardiac muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000298552 TSC1-001 protein_coding Homo_sapiens 0 3986
ENST00000403810 TSC1-003 protein_coding Homo_sapiens 0 1474
ENST00000440111 TSC1-201 protein_coding Homo_sapiens 0 3788
ENST00000475903 TSC1-005 processed_transcript Homo_sapiens 0 815
ENST00000490179 TSC1-002 processed_transcript Homo_sapiens 0 473
ENST00000493467 TSC1-006 retained_intron Homo_sapiens 0 1646
ENST00000545250 TSC1-202 protein_coding Homo_sapiens 0 3321

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