C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BRCA1/BRCA2-containing complex, subunit 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000114074 Brcc3-004 ENSMUSG00000031201 10090 + X:75416710-75451708 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000114074
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000114074 1.971±0.27 3.565±0.05 3.078±0.12 1.331±0.12 2.296±0.98 2.214±1.02 3.045±0.58 2.982±1.20 1.700±0.26 1.216±0.24 1.141±0.49 1.268±0.66 0.422±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003LJ CIL_0003LJ_0002 CGP X:75416628-75534942

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004221 ISS ubiquitin thiolesterase activity
GO:0004843 ISS ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006302 ISS double-strand break repair
GO:0006508 IEA proteolysis
GO:0008237 ISS metallopeptidase activity
GO:0010212 ISS response to ionizing radiation
GO:0031572 ISS G2 DNA damage checkpoint
GO:0031593 ISS polyubiquitin binding
GO:0045739 ISS positive regulation of DNA repair
GO:0046872 IEA metal ion binding
GO:0070531 ISS BRCA1-A complex
GO:0070536 ISS protein K63-linked deubiquitination
GO:0070537 ISS histone H2A K63-linked deubiquitination
GO:0070552 ISS BRISC complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000330045 BRCC3-002 protein_coding Homo_sapiens 0 1225
ENST00000340647 BRCC3-006 protein_coding Homo_sapiens 0 1212
ENST00000369459 BRCC3-004 protein_coding Homo_sapiens 0 774
ENST00000369462 BRCC3-001 protein_coding Homo_sapiens 0 778
ENST00000399026 BRCC3-003 protein_coding Homo_sapiens 0 307
ENST00000399042 BRCC3-201 protein_coding Homo_sapiens 0 761
ENST00000411985 BRCC3-007 protein_coding Homo_sapiens 0 523
ENST00000453705 BRCC3-005 nonsense_mediated_decay Homo_sapiens 0 1164
ENST00000508559 RP11-844P9.3-001 processed_pseudogene Homo_sapiens 0 712
ENST00000620502 BRCC3-202 protein_coding Homo_sapiens 0 1175

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