C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 1A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000116273 Kdm1a-001 ENSMUSG00000036940 10090 - 4:136550540-136602723 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000116273
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000116273 5.342±1.86 4.235±0.96 6.859±0.90 18.549±12.23 4.845±2.50 7.546±1.64 2.813±0.55 2.534±1.01 4.390±3.03 5.738±2.63 2.269±0.66 9.186±3.57 10.425±4.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000208 CIL_000208_0002 CGP 4:136469761-136602723

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001701 IMP in utero embryonic development
GO:0002039 IEA p53 binding
GO:0003682 ISS chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005667 IDA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0006482 IEA protein demethylation
GO:0008134 IPI transcription factor binding
GO:0008283 IMP cell proliferation
GO:0010725 IMP regulation of primitive erythrocyte differentiation
GO:0016491 ISS oxidoreductase activity
GO:0019899 IPI enzyme binding
GO:0021983 IMP pituitary gland development
GO:0030374 ISS ligand-dependent nuclear receptor transcription coactivator activity
GO:0030851 IMP granulocyte differentiation
GO:0032091 IEA negative regulation of protein binding
GO:0032451 IEA demethylase activity
GO:0032452 ISS histone demethylase activity
GO:0032453 ISS histone demethylase activity (H3-K4 specific)
GO:0032454 ISS histone demethylase activity (H3-K9 specific)
GO:0033169 ISS histone H3-K9 demethylation
GO:0034401 IC regulation of transcription by chromatin organization
GO:0034648 ISS histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 ISS histone H3-K4 demethylation
GO:0043426 IPI MRF binding
GO:0043433 ISS negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043518 IEA negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0045654 IMP positive regulation of megakaryocyte differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046886 IMP positive regulation of hormone biosynthetic process
GO:0050660 ISS flavin adenine dinucleotide binding
GO:0050681 ISS androgen receptor binding
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051572 IMP negative regulation of histone H3-K4 methylation
GO:0051573 IMP negative regulation of histone H3-K9 methylation
GO:0055001 IMP muscle cell development
GO:0055114 IEA oxidation-reduction process
GO:1902166 IEA negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000179 IMP positive regulation of neural precursor cell proliferation
GO:2000648 IMP positive regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000356634 KDM1A-001 protein_coding Homo_sapiens 0 3441
ENST00000400181 KDM1A-002 protein_coding Homo_sapiens 0 2765
ENST00000465864 KDM1A-005 protein_coding Homo_sapiens 0 701
ENST00000481879 KDM1A-003 retained_intron Homo_sapiens 0 309
ENST00000494920 KDM1A-004 protein_coding Homo_sapiens 0 1090
ENST00000602503 KDM1A-006 retained_intron Homo_sapiens 0 220

Loading