C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin alpha L
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000117762 Itgal-002 ENSMUSG00000030830 10090 + 7:127296260-127335137 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000117762
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000117762 1.897±1.14 0.382±0.00 0.067±0.01 6.231±1.58 1.090±0.02 0.567±0.15 1.794±0.00 0.769±0.15 3.360±0.00 0.706±0.00 0.970±0.42 0.149±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000U7 CIL_0000U7_0002 CGP 7:127296260-127345314

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0005911 IDA cell-cell junction
GO:0007159 IDA leukocyte cell-cell adhesion
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008305 IEA integrin complex
GO:0009897 IDA external side of plasma membrane
GO:0022407 IDA regulation of cell-cell adhesion
GO:0022409 IMP positive regulation of cell-cell adhesion
GO:0042102 IMP positive regulation of T cell proliferation
GO:0050798 IMP activated T cell proliferation
GO:0050850 IDA positive regulation of calcium-mediated signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000356798 ITGAL-001 protein_coding Homo_sapiens 0 2237
ENST00000358164 ITGAL-002 protein_coding Homo_sapiens 0 1943
ENST00000433423 ITGAL-004 protein_coding Homo_sapiens 0 547
ENST00000564632 ITGAL-023 retained_intron Homo_sapiens 4.99997e-41 172
ENST00000568987 ITGAL-018 retained_intron Homo_sapiens 7e-27 124

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