C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000358164 ITGAL-002 ENSG00000005844 9606 + 16:30472729-30522968 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastHeartLiverMuscleOvaryPlacentaTestisENST00000358164
Transcript ID Adipose Adrenal Breast Heart Liver Muscle Ovary Placenta Testis
ENST00000358164 0.750±0.00 5.006±0.00 0.812±0.00 0.038±0.00 0.698±0.00 0.087±0.00 0.580±0.00 1.301±0.65 0.398±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000U7 CIL_0000U7_0001 CGP 16:30472658-30526821

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002291 IMP T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0006928 TAS cellular component movement
GO:0006954 NAS inflammatory response
GO:0007155 NAS cell adhesion
GO:0007157 IMP heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 IMP leukocyte cell-cell adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007165 NAS signal transduction
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007596 TAS blood coagulation
GO:0008305 NAS integrin complex
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0030198 TAS extracellular matrix organization
GO:0030369 IMP ICAM-3 receptor activity
GO:0034687 IDA integrin alphaL-beta2 complex
GO:0043113 IMP receptor clustering
GO:0046872 IEA metal ion binding
GO:0050776 TAS regulation of immune response
GO:0050839 IPI cell adhesion molecule binding
GO:0050900 TAS leukocyte migration
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000106306 Itgal-001 protein_coding Mus_musculus 0 1958
ENSMUST00000170971 Itgal-201 protein_coding Mus_musculus 0 1943
ENSMUST00000117762 Itgal-002 protein_coding Mus_musculus 0 1943
ENSMUST00000120857 Itgal-003 protein_coding Mus_musculus 0 1840
ENSMUST00000118405 Itgal-004 protein_coding Mus_musculus 0 1502

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