C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin alpha L
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000118405 Itgal-004 ENSMUSG00000030830 10090 + 7:127309518-127335137 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000118405
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000118405 1.505±0.29 0.433±0.29 0.518±0.23 0.116±0.01 10.611±1.17 1.031±0.10 0.441±0.13 0.956±0.36 2.092±1.12 7.907±0.60 0.071±0.03 0.869±0.43 0.167±0.04 0.235±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000U7 CIL_0000U7_0002 CGP 7:127296260-127345314

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0005911 IDA cell-cell junction
GO:0007159 IDA leukocyte cell-cell adhesion
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008305 IEA integrin complex
GO:0009897 IDA external side of plasma membrane
GO:0022407 IDA regulation of cell-cell adhesion
GO:0022409 IMP positive regulation of cell-cell adhesion
GO:0042102 IMP positive regulation of T cell proliferation
GO:0050798 IMP activated T cell proliferation
GO:0050850 IDA positive regulation of calcium-mediated signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000356798 ITGAL-001 protein_coding Homo_sapiens 0 1498
ENST00000358164 ITGAL-002 protein_coding Homo_sapiens 0 1502
ENST00000433423 ITGAL-004 protein_coding Homo_sapiens 0 547
ENST00000564632 ITGAL-023 retained_intron Homo_sapiens 4.99997e-41 172
ENST00000568987 ITGAL-018 retained_intron Homo_sapiens 7e-27 124

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