C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WW domain containing transcription regulator 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000465804 WWTR1-001 ENSG00000018408 9606 - 3:149517235-149703273 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderOvaryPlacentaTestisENST00000465804
Transcript ID Bladder Ovary Placenta Testis
ENST00000465804 1.696±0.00 13.824±0.00 2.403±0.00 0.750±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002R1 CIL_0002R1_0001 CGP 3:149473974-149736714
CIL_0002R8 CIL_0002R8_0001 CGP 3:149517235-149752499

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001649 IEA osteoblast differentiation
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0003713 NAS transcription coactivator activity
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 TAS transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006469 IMP negative regulation of protein kinase activity
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0010467 TAS gene expression
GO:0010718 IDA positive regulation of epithelial to mesenchymal transition
GO:0016567 IEA protein ubiquitination
GO:0017145 IDA stem cell division
GO:0031146 IEA SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032835 IEA glomerulus development
GO:0035264 IEA multicellular organism growth
GO:0035329 IDA hippo signaling
GO:0035414 IMP negative regulation of catenin import into nucleus
GO:0042803 IEA protein homodimerization activity
GO:0045599 IEA negative regulation of fat cell differentiation
GO:0045944 TAS positive regulation of transcription from RNA polymerase II promoter
GO:0048762 IEA mesenchymal cell differentiation
GO:0060271 IEA cilium morphogenesis
GO:0060390 IDA regulation of SMAD protein import into nucleus
GO:0060828 IEA regulation of canonical Wnt signaling pathway
GO:0060993 IEA kidney morphogenesis
GO:0072307 IEA regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029380 Wwtr1-001 protein_coding Mus_musculus 0 1650
ENSMUST00000120977 Wwtr1-002 protein_coding Mus_musculus 0 1648

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