C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tuberous sclerosis 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000133565 Tsc1-004 ENSMUSG00000026812 10090 + 2:28641241-28688548 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryPlacentaTestisENSMUST00000133565
Transcript ID Brain Ovary Placenta Testis
ENSMUST00000133565 7.317±0.00 1.771±0.00 3.350±1.54 3.741±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000H4 CIL_0000H4_0002 CGP 2:28609450-28691167
CIL_0002XC CIL_0002XC_0002 CGP 2:28641228-28699727

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0001843 IMP neural tube closure
GO:0005737 IDA cytoplasm
GO:0006813 IGI potassium ion transport
GO:0007399 IMP nervous system development
GO:0008285 IMP negative regulation of cell proliferation
GO:0021766 IMP hippocampus development
GO:0021987 IMP cerebral cortex development
GO:0030030 IMP cell projection organization
GO:0030695 IBA GTPase regulator activity
GO:0032007 IBA negative regulation of TOR signaling
GO:0032318 IBA regulation of Ras GTPase activity
GO:0032956 IBA regulation of actin cytoskeleton organization
GO:0033596 IBA TSC1-TSC2 complex
GO:0042552 IMP myelination
GO:0045792 IGI negative regulation of cell size
GO:0045859 IGI regulation of protein kinase activity
GO:0046323 IMP glucose import
GO:0046627 IBA negative regulation of insulin receptor signaling pathway
GO:0050808 IMP synapse organization
GO:0051726 IBA regulation of cell cycle
GO:0055007 IMP cardiac muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000298552 TSC1-001 protein_coding Homo_sapiens 0 4063
ENST00000403810 TSC1-003 protein_coding Homo_sapiens 0 1478
ENST00000440111 TSC1-201 protein_coding Homo_sapiens 0 3862
ENST00000475903 TSC1-005 processed_transcript Homo_sapiens 0 815
ENST00000490179 TSC1-002 processed_transcript Homo_sapiens 0 473
ENST00000493467 TSC1-006 retained_intron Homo_sapiens 0 1666
ENST00000545250 TSC1-202 protein_coding Homo_sapiens 0 3395

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