C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin-like growth factor binding protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000135887 Igfbp3-002 ENSMUSG00000020427 10090 - 11:7207686-7213923 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungOvaryENSMUST00000135887
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Ovary
ENSMUST00000135887 4.445±0.00 94.450±20.90 1.973±0.90 22.969±9.43 26.867±7.00 65.644±0.00 4.279±1.38 14.717±10.63 52.278±12.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WT CIL_0008WT_0002 VISTA 11:6754211-7357799
CIL_0005P5 CIL_0005P5_0003 CGP 11:7197782-7213923
CIL_0000S7 CIL_0000S7_0002 CGP 11:7206086-8664535

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001558 IGI regulation of cell growth
GO:0001649 IEP osteoblast differentiation
GO:0001933 ISO negative regulation of protein phosphorylation
GO:0001968 IDA fibronectin binding
GO:0005520 IPI insulin-like growth factor binding
GO:0005615 IDA extracellular space
GO:0005634 ISO nucleus
GO:0006468 ISO protein phosphorylation
GO:0008160 ISS protein tyrosine phosphatase activator activity
GO:0010906 IGI regulation of glucose metabolic process
GO:0040008 IGI regulation of growth
GO:0043065 ISS positive regulation of apoptotic process
GO:0043410 IGI positive regulation of MAPK cascade
GO:0043568 IGI positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044342 IGI type B pancreatic cell proliferation
GO:0045663 ISS positive regulation of myoblast differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000275521 IGFBP3-001 protein_coding Homo_sapiens 0 808
ENST00000381083 IGFBP3-020 protein_coding Homo_sapiens 0 747
ENST00000381086 IGFBP3-008 protein_coding Homo_sapiens 0 536
ENST00000417621 IGFBP3-019 protein_coding Homo_sapiens 0 492
ENST00000428530 IGFBP3-018 protein_coding Homo_sapiens 0 484
ENST00000448817 IGFBP3-014 protein_coding Homo_sapiens 0 327
ENST00000613132 IGFBP3-201 protein_coding Homo_sapiens 0 723
ENST00000615754 IGFBP3-202 protein_coding Homo_sapiens 0 708

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