C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: chemokine (C-X-C motif) receptor 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000142893 Cxcr4-002 ENSMUSG00000045382 10090 - 1:128589099-128592293 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000142893
Transcript ID Bladder Brain Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000142893 1.184±0.00 7.834±0.00 1.938±0.03 1.345±0.00 2.048±1.95 31.258±0.00 0.555±0.10 3.818±0.59 1.286±0.51 1.617±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00077L CIL_00077L_0002 CGP 1:128363707-128592293
CIL_0006VZ CIL_0006VZ_0002 CGP 1:128588199-130219278

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001569 IMP patterning of blood vessels
GO:0001667 IMP ameboidal cell migration
GO:0001764 IDA neuron migration
GO:0005911 IDA cell-cell junction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007281 IMP germ cell development
GO:0007420 IMP brain development
GO:0008045 IMP motor neuron axon guidance
GO:0008354 IMP germ cell migration
GO:0009897 IDA external side of plasma membrane
GO:0009986 ISO cell surface
GO:0016021 IEA integral component of membrane
GO:0016494 IEA C-X-C chemokine receptor activity
GO:0019722 ISO calcium-mediated signaling
GO:0019955 IEA cytokine binding
GO:0030334 IMP regulation of cell migration
GO:0030426 IDA growth cone
GO:0042098 IMP T cell proliferation
GO:0042119 IEA neutrophil activation
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000241393 CXCR4-001 protein_coding Homo_sapiens 0 865
ENST00000409817 CXCR4-003 protein_coding Homo_sapiens 0 839
ENST00000466288 CXCR4-002 processed_transcript Homo_sapiens 0 837

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