C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Wilms tumor 1 homolog
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000143043 Wt1-001 ENSMUSG00000016458 10090 + 2:105126529-105173612 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000143043
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000143043 10.166±9.03 0.238±0.10 0.706±0.32 0.018±0.00 0.163±0.07 0.495±0.13 1.802±0.24 0.235±0.18 0.658±0.26 13.242±4.28 0.789±0.60 4.622±0.62

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SB CIL_0008SB_0002 VISTA 2:104593780-105194712
CIL_0008NI CIL_0008NI_0002 VISTA 2:105033715-105635145

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISO negative regulation of transcription from RNA polymerase II promoter
GO:0001570 IMP vasculogenesis
GO:0001656 IMP metanephros development
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001822 IEA kidney development
GO:0001823 IMP mesonephros development
GO:0003690 IDA double-stranded DNA binding
GO:0003723 IDA RNA binding
GO:0005515 IEA protein binding
GO:0005654 IEA nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006915 IMP apoptotic process
GO:0007281 IMP germ cell development
GO:0007283 IMP spermatogenesis
GO:0007338 IMP single fertilization
GO:0007507 IEA heart development
GO:0007530 IMP sex determination
GO:0008270 IEA zinc ion binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0008584 IMP male gonad development
GO:0009888 IMP tissue development
GO:0010468 IMP regulation of gene expression
GO:0016607 IEA nuclear speck
GO:0017148 IEA negative regulation of translation
GO:0030308 IEA negative regulation of cell growth
GO:0030317 IMP sperm motility
GO:0030325 IEA adrenal gland development
GO:0032835 IEA glomerulus development
GO:0032836 IEA glomerular basement membrane development
GO:0043010 IMP camera-type eye development
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0060009 IMP Sertoli cell development
GO:0061032 IEA visceral serous pericardium development
GO:0070742 IEA C2H2 zinc finger domain binding
GO:0071320 IBA cellular response to cAMP
GO:0071371 IBA cellular response to gonadotropin stimulus
GO:0072207 IEA metanephric epithelium development
GO:0072284 IEA metanephric S-shaped body morphogenesis
GO:0072520 IMP seminiferous tubule development
GO:1900212 IMP negative regulation of mesenchymal cell apoptotic process involved in metanephros development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000332351 WT1-001 protein_coding Homo_sapiens 0 2532
ENST00000379077 WT1-005 nonsense_mediated_decay Homo_sapiens 0 1190
ENST00000379079 WT1-002 protein_coding Homo_sapiens 0 1543
ENST00000448076 WT1-009 protein_coding Homo_sapiens 0 2100
ENST00000452863 WT1-004 protein_coding Homo_sapiens 0 1046
ENST00000526685 WT1-007 protein_coding Homo_sapiens 0 315
ENST00000527775 WT1-006 protein_coding Homo_sapiens 0 651
ENST00000527882 WT1-008 protein_coding Homo_sapiens 0 453
ENST00000530998 WT1-003 protein_coding Homo_sapiens 0 1103

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