C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Wilms tumor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000332351 WT1-001 ENSG00000184937 9606 - 11:32387775-32435630 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderLiverOvaryPlacentaENST00000332351
Transcript ID Bladder Liver Ovary Placenta
ENST00000332351 0.327±0.00 0.025±0.00 13.872±12.80 1.057±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NI CIL_0008NI_0001 VISTA 11:31875944-32477188
CIL_0004RH CIL_0004RH_0002 CGP 11:32387775-32606262

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001570 ISS vasculogenesis
GO:0001656 IEA metanephros development
GO:0001657 ISS ureteric bud development
GO:0001658 IGI branching involved in ureteric bud morphogenesis
GO:0001822 IGI kidney development
GO:0001823 IEA mesonephros development
GO:0003156 ISS regulation of organ formation
GO:0003690 IEA double-stranded DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IDA:ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS:IEA regulation of transcription, DNA-templated
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0006915 IEA apoptotic process
GO:0007281 ISS germ cell development
GO:0007283 IEA spermatogenesis
GO:0007338 IEA single fertilization
GO:0007356 ISS thorax and anterior abdomen determination
GO:0007507 IGI heart development
GO:0007530 IDA sex determination
GO:0008270 IDA zinc ion binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0008380 ISS RNA splicing
GO:0008406 ISS gonad development
GO:0008584 IEP male gonad development
GO:0009888 ISS tissue development
GO:0010468 IEA regulation of gene expression
GO:0016607 IDA nuclear speck
GO:0017148 IDA negative regulation of translation
GO:0030308 IDA negative regulation of cell growth
GO:0030317 IEA sperm motility
GO:0030325 IGI adrenal gland development
GO:0030539 ISS male genitalia development
GO:0030855 ISS epithelial cell differentiation
GO:0032835 IGI glomerulus development
GO:0032836 IMP glomerular basement membrane development
GO:0035802 ISS adrenal cortex formation
GO:0043010 ISS camera-type eye development
GO:0043065 IDA positive regulation of apoptotic process
GO:0043066 IGI negative regulation of apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IGI positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0060009 IEA Sertoli cell development
GO:0060231 ISS mesenchymal to epithelial transition
GO:0060421 ISS positive regulation of heart growth
GO:0060539 ISS diaphragm development
GO:0060923 ISS cardiac muscle cell fate commitment
GO:0061032 IGI visceral serous pericardium development
GO:0070742 IPI C2H2 zinc finger domain binding
GO:0071320 IEP cellular response to cAMP
GO:0071371 IDA cellular response to gonadotropin stimulus
GO:0072075 ISS metanephric mesenchyme development
GO:0072112 ISS glomerular visceral epithelial cell differentiation
GO:0072166 ISS posterior mesonephric tubule development
GO:0072207 IEP metanephric epithelium development
GO:0072284 IGI metanephric S-shaped body morphogenesis
GO:0072302 ISS negative regulation of metanephric glomerular mesangial cell proliferation
GO:0072520 IEA seminiferous tubule development
GO:1900212 IEA negative regulation of mesenchymal cell apoptotic process involved in metanephros development
GO:2000020 ISS positive regulation of male gonad development
GO:2000195 ISS negative regulation of female gonad development
GO:2001076 ISS positive regulation of metanephric ureteric bud development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000143043 Wt1-001 protein_coding Mus_musculus 0 2532
ENSMUST00000111099 Wt1-006 protein_coding Mus_musculus 0 1546
ENSMUST00000111098 Wt1-008 protein_coding Mus_musculus 0 1103
ENSMUST00000133470 Wt1-002 protein_coding Mus_musculus 0 924
ENSMUST00000146842 Wt1-003 protein_coding Mus_musculus 0 806
ENSMUST00000139585 Wt1-004 protein_coding Mus_musculus 0 802
ENSMUST00000153944 Wt1-009 retained_intron Mus_musculus 0 603

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