C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MKL/myocardin-like 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000149359 Mkl2-001 ENSMUSG00000009569 10090 + 16:13358421-13417529 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000149359
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000149359 3.075±2.36 3.439±0.68 1.317±0.00 5.890±3.72 2.597±1.45 2.803±1.32 1.135±0.00 0.566±0.25 0.835±0.50 6.321±1.80 1.188±0.60 3.356±1.64 3.317±1.00 3.247±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002RP CIL_0002RP_0003 CGP 16:13109684-13417529
CIL_0007DW CIL_0007DW_0002 CGP 16:13256481-13668170

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0003007 IMP heart morphogenesis
GO:0003676 IEA nucleic acid binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003779 IDA actin binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0007507 IMP heart development
GO:0010467 IMP gene expression
GO:0010468 IMP regulation of gene expression
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048514 IMP blood vessel morphogenesis
GO:0048568 IMP embryonic organ development
GO:0048738 IMP cardiac muscle tissue development
GO:0051145 IMP smooth muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000153177 mkl2a-001 protein_coding Danio_rerio 0.000000000004 79
ENSDART00000127655 mkl2a-201 protein_coding Danio_rerio 0.000000000003 79
ENSDART00000112456 MKL2 (1 of 3)-201 protein_coding Danio_rerio 0.000000000003 79
ENST00000318282 MKL2-201 protein_coding Homo_sapiens 0 1079
ENST00000355630 MKL1-001 protein_coding Homo_sapiens 0 255
ENST00000396617 MKL1-201 protein_coding Homo_sapiens 0 255
ENST00000402042 MKL1-002 protein_coding Homo_sapiens 0 255
ENST00000402630 MKL1-009 protein_coding Homo_sapiens 0 241
ENST00000407029 MKL1-003 protein_coding Homo_sapiens 0 255
ENST00000571589 MKL2-001 protein_coding Homo_sapiens 0 1860
ENST00000571770 MKL2-012 nonsense_mediated_decay Homo_sapiens 0 625
ENST00000572567 MKL2-004 protein_coding Homo_sapiens 0 1338
ENST00000572588 MKL2-006 retained_intron Homo_sapiens 0 957
ENST00000573051 MKL2-005 protein_coding Homo_sapiens 0 1077
ENST00000574045 MKL2-002 protein_coding Homo_sapiens 0 1079
ENST00000574998 MKL2-007 protein_coding Homo_sapiens 1e-19 100
ENST00000575768 MKL2-011 processed_transcript Homo_sapiens 0 274
ENST00000614754 MKL1-202 protein_coding Homo_sapiens 0 239
ENST00000618196 MKL1-203 protein_coding Homo_sapiens 0 255
ENST00000620651 MKL1-205 protein_coding Homo_sapiens 0 239

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