C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenergic receptor, alpha 1a
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000159365 Adra1a-001 ENSMUSG00000045875 10090 + 14:66635251-66733462 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000159365
Transcript ID Adrenal Bladder Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000159365 1.049±0.30 0.014±0.00 1.728±0.59 0.085±0.04 2.235±0.70 0.427±0.23 2.074±0.00 0.178±0.11 0.287±0.24 0.009±0.00 0.004±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001985 IMP negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
GO:0001994 IMP norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0001996 IGI positive regulation of heart rate by epinephrine-norepinephrine
GO:0001997 IGI positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0004937 ISO alpha1-adrenergic receptor activity
GO:0005886 IEA plasma membrane
GO:0007200 IDA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007512 IGI adult heart development
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016049 IGI cell growth
GO:0019229 IEA regulation of vasoconstriction
GO:0035024 ISO negative regulation of Rho protein signal transduction
GO:0035265 IGI organ growth
GO:0043410 IGI positive regulation of MAPK cascade
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0071875 IEA adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000276393 ADRA1A-003 protein_coding Homo_sapiens 0 1511
ENST00000354550 ADRA1A-002 protein_coding Homo_sapiens 0 1478
ENST00000380572 ADRA1A-005 protein_coding Homo_sapiens 0 1085
ENST00000380573 ADRA1A-008 protein_coding Homo_sapiens 0 1511
ENST00000380582 ADRA1A-001 protein_coding Homo_sapiens 0 1513
ENST00000380586 ADRA1A-004 protein_coding Homo_sapiens 0 1509
ENST00000519096 ADRA1A-007 nonsense_mediated_decay Homo_sapiens 0 1088
ENST00000519229 ADRA1A-009 protein_coding Homo_sapiens 0 1448
ENST00000521711 ADRA1A-006 nonsense_mediated_decay Homo_sapiens 0 1088

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