C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenoceptor alpha 1A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354550 ADRA1A-002 ENSG00000120907 9606 - 8:26765854-26865169 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastLungOvaryTestisENST00000354550
Transcript ID Adipose Adrenal Breast Lung Ovary Testis
ENST00000354550 0.406±0.00 0.351±0.00 0.304±0.00 0.374±0.00 0.164±0.00 0.261±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TP CIL_0005TP_0002 CGP 8:26514275-26867273

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004937 ISS alpha1-adrenergic receptor activity
GO:0005634 IDA nucleus
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006915 TAS apoptotic process
GO:0006939 TAS smooth muscle contraction
GO:0007165 TAS signal transduction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007202 ISS activation of phospholipase C activity
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0007267 TAS cell-cell signaling
GO:0007568 ISS aging
GO:0008285 TAS negative regulation of cell proliferation
GO:0009725 ISS response to hormone
GO:0016021 IEA integral component of membrane
GO:0031965 IDA nuclear membrane
GO:0032229 ISS negative regulation of synaptic transmission, GABAergic
GO:0035024 ISS negative regulation of Rho protein signal transduction
GO:0035556 TAS intracellular signal transduction
GO:0042493 ISS response to drug
GO:0043410 IDA positive regulation of MAPK cascade
GO:0045760 ISS positive regulation of action potential
GO:0045907 ISS positive regulation of vasoconstriction
GO:0046982 IDA protein heterodimerization activity
GO:0060402 ISS calcium ion transport into cytosol
GO:0060452 ISS positive regulation of cardiac muscle contraction
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0071875 IEA adrenergic receptor signaling pathway
GO:0090037 ISS positive regulation of protein kinase C signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000159068 Adra1a-004 protein_coding Mus_musculus 0 1478
ENSMUST00000054661 Adra1a-002 protein_coding Mus_musculus 0 1478
ENSMUST00000159365 Adra1a-001 protein_coding Mus_musculus 0 1478
ENSMUST00000161339 Adra1a-003 protein_coding Mus_musculus 0 1456
ENSMUST00000160647 Adra1a-005 retained_intron Mus_musculus 0 1055

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