C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: runt related transcription factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000162816 Runx2-008 ENSMUSG00000039153 10090 - 17:44495987-44736176 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartKidneyLungMuscleTestisENSMUST00000162816
Transcript ID Adipose Brain Colon Heart Kidney Lung Muscle Testis
ENSMUST00000162816 0.093±0.00 0.310±0.23 0.179±0.01 0.039±0.00 0.109±0.00 0.343±0.00 0.047±0.00 0.517±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VA CIL_0007VA_0002 VISTA 17:43996915-44602724
CIL_0002LE CIL_0002LE_0002 CGP 17:44188572-44814797
CIL_00082L CIL_00082L_0002 VISTA 17:44317720-44919644
CIL_0007Z9 CIL_0007Z9_0002 VISTA 17:44422114-45023789

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001501 IMP skeletal system development
GO:0001649 IMP osteoblast differentiation
GO:0001958 IMP endochondral ossification
GO:0002051 IGI osteoblast fate commitment
GO:0002062 IGI chondrocyte differentiation
GO:0002063 IMP chondrocyte development
GO:0002076 IGI osteoblast development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0008284 IMP positive regulation of cell proliferation
GO:0010628 IDA positive regulation of gene expression
GO:0019904 IPI protein domain specific binding
GO:0030217 IDA T cell differentiation
GO:0030278 IMP regulation of ossification
GO:0032332 IMP positive regulation of chondrocyte differentiation
GO:0035115 IMP embryonic forelimb morphogenesis
GO:0040036 IMP regulation of fibroblast growth factor receptor signaling pathway
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0042487 IMP regulation of odontogenesis of dentin-containing tooth
GO:0043425 IPI bHLH transcription factor binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045667 IDA regulation of osteoblast differentiation
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045879 IMP negative regulation of smoothened signaling pathway
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IGI cell maturation
GO:0048701 IGI embryonic cranial skeleton morphogenesis
GO:0048705 IMP skeletal system morphogenesis
GO:0048863 IDA stem cell differentiation
GO:0070491 IPI repressing transcription factor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000359524 RUNX2-001 protein_coding Homo_sapiens 0 970
ENST00000371432 RUNX2-201 protein_coding Homo_sapiens 0 813
ENST00000371436 RUNX2-004 protein_coding Homo_sapiens 0 813
ENST00000371438 RUNX2-003 protein_coding Homo_sapiens 0 813
ENST00000465038 RUNX2-002 protein_coding Homo_sapiens 0 813
ENST00000478660 RUNX2-009 nonsense_mediated_decay Homo_sapiens 0 1738
ENST00000483377 RUNX2-007 nonsense_mediated_decay Homo_sapiens 0 342
ENST00000576263 RUNX2-008 protein_coding Homo_sapiens 0 813

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