C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor receptor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000164207 Fgfr3-008 ENSMUSG00000054252 10090 + 5:33721791-33737063 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000164207
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000164207 1.952±0.53 0.590±0.29 6.534±0.79 1.201±0.37 4.293±0.57 0.728±0.16 7.062±1.73 1.145±0.96 32.732±4.27 0.230±0.00 2.315±1.19 1.234±0.60 0.929±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TX CIL_0007TX_0002 VISTA 5:33275293-33875875
CIL_0006V2 CIL_0006V2_0002 CGP 5:33658128-33737068
CIL_0006V3 CIL_0006V3_0002 CGP 5:33721724-33782817

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000165 IDA MAPK cascade
GO:0001938 IMP positive regulation of endothelial cell proliferation
GO:0002009 IMP morphogenesis of an epithelium
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0005007 IDA fibroblast growth factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005764 IDA lysosome
GO:0005887 IEA integral component of plasma membrane
GO:0007267 IEA cell-cell signaling
GO:0008284 IGI positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0008543 IDA fibroblast growth factor receptor signaling pathway
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0009986 IEA cell surface
GO:0010518 IEA positive regulation of phospholipase activity
GO:0014003 IMP oligodendrocyte development
GO:0016021 IEA integral component of membrane
GO:0017134 IEA fibroblast growth factor binding
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021762 IMP substantia nigra development
GO:0022010 IMP central nervous system myelination
GO:0030154 IMP cell differentiation
GO:0030900 IMP forebrain development
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0035019 IMP somatic stem cell maintenance
GO:0042511 IEA positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517 IEA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043410 IMP positive regulation of MAPK cascade
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0043552 IEA positive regulation of phosphatidylinositol 3-kinase activity
GO:0045597 IMP positive regulation of cell differentiation
GO:0045839 IGI negative regulation of mitosis
GO:0045879 IMP negative regulation of smoothened signaling pathway
GO:0046777 IEA protein autophosphorylation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048546 IMP digestive tract morphogenesis
GO:0048678 IMP response to axon injury
GO:0048712 IMP negative regulation of astrocyte differentiation
GO:0048839 IMP inner ear development
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0051216 IMP cartilage development
GO:0060113 IMP inner ear receptor cell differentiation
GO:0060349 IMP bone morphogenesis
GO:0060385 IMP axonogenesis involved in innervation
GO:0061144 IGI alveolar secondary septum development
GO:0070307 IGI lens fiber cell development
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0072148 IMP epithelial cell fate commitment
GO:0090080 IGI positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0090102 IMP cochlea development
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:1902178 IEA fibroblast growth factor receptor apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000260795 FGFR3-001 protein_coding Homo_sapiens 0 2543
ENST00000340107 FGFR3-201 protein_coding Homo_sapiens 0 911
ENST00000352904 FGFR3-002 protein_coding Homo_sapiens 0 872
ENST00000412135 FGFR3-202 protein_coding Homo_sapiens 0 911
ENST00000440486 FGFR3-203 protein_coding Homo_sapiens 0 2543
ENST00000474521 FGFR3-004 processed_transcript Homo_sapiens 0 388
ENST00000481110 FGFR3-006 protein_coding Homo_sapiens 0 2084
ENST00000507588 FGFR3-007 protein_coding Homo_sapiens 0 350
ENST00000613647 FGFR3-204 protein_coding Homo_sapiens 0 1637

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