C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000169202 Hmgcr-004 ENSMUSG00000021670 10090 - 13:96652121-96656667 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainOvaryPlacentaTestisENSMUST00000169202
Transcript ID Adrenal Brain Ovary Placenta Testis
ENSMUST00000169202 9.872±0.00 52.275±0.00 82.849±0.00 82.708±0.00 49.339±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XB CIL_0002XB_0003 CGP 13:96542618-96670936

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004420 IDA hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0006695 IDA cholesterol biosynthetic process
GO:0008542 IGI visual learning
GO:0015936 IEA coenzyme A metabolic process
GO:0043407 IGI negative regulation of MAP kinase activity
GO:0050662 IEA coenzyme binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000287936 HMGCR-001 protein_coding Homo_sapiens 0 630
ENST00000343975 HMGCR-004 protein_coding Homo_sapiens 0 736
ENST00000508070 HMGCR-011 retained_intron Homo_sapiens 0 337
ENST00000511206 HMGCR-002 protein_coding Homo_sapiens 0 630

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