C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sine oculis-related homeobox 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000175898 Six3-002 ENSMUSG00000038805 10090 + 17:85613608-85625222 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainHeartLiverLungPlacentaENSMUST00000175898
Transcript ID Bladder Brain Heart Liver Lung Placenta
ENSMUST00000175898 0.003±0.00 4.163±3.05 0.026±0.02 0.022±0.00 0.012±0.00 0.061±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001NM CIL_0001NM_0002 CGP 17:85090726-85629302
CIL_0007KD CIL_0007KD_0002 UCNEbase 17:85172000-86036297
CIL_00083B CIL_00083B_0002 VISTA 17:85187468-85789670
CIL_0009CD CIL_0009CD_0002 VISTA 17:85226742-85830634
CIL_0009CC CIL_0009CC_0002 VISTA 17:85262619-85863333
CIL_0007WX CIL_0007WX_0002 VISTA 17:85278835-85879978
CIL_0001NN CIL_0001NN_0002 CGP 17:85613608-85688274

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 IDA protein import into nucleus, translocation
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001205 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001222 IPI transcription corepressor binding
GO:0001654 IDA eye development
GO:0002070 IMP epithelial cell maturation
GO:0002088 IDA lens development in camera-type eye
GO:0003404 IDA optic vesicle morphogenesis
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006606 IDA protein import into nucleus
GO:0007420 IMP brain development
GO:0009946 IDA proximal/distal axis specification
GO:0014016 IMP neuroblast differentiation
GO:0021536 IGI diencephalon development
GO:0021537 IMP telencephalon development
GO:0021797 IGI forebrain anterior/posterior pattern specification
GO:0021798 ISS forebrain dorsal/ventral pattern formation
GO:0021846 IMP cell proliferation in forebrain
GO:0021978 IMP telencephalon regionalization
GO:0021983 IMP pituitary gland development
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0042127 IMP regulation of cell proliferation
GO:0042826 IPI histone deacetylase binding
GO:0043010 IGI camera-type eye development
GO:0043565 IDA sequence-specific DNA binding
GO:0045665 IDA negative regulation of neuron differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048512 IMP circadian behavior
GO:0060235 IMP lens induction in camera-type eye
GO:0061074 IMP regulation of neural retina development
GO:0070306 IDA lens fiber cell differentiation
GO:0097402 IMP neuroblast migration
GO:1901987 IDA regulation of cell cycle phase transition
GO:1902692 IMP regulation of neuroblast proliferation
GO:1902742 IMP apoptotic process involved in development
GO:1990086 IDA lens fiber cell apoptotic process
GO:2000177 IDA regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000260653 SIX3-001 protein_coding Homo_sapiens 0 2715
ENST00000327720 SIX6-001 protein_coding Homo_sapiens 0 479

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