C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: rho/rac guanine nucleotide exchange factor (GEF) 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000177498 Arhgef2-002 ENSMUSG00000028059 10090 + 3:88616143-88647532 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLungMuscleOvaryENSMUST00000177498
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Lung Muscle Ovary
ENSMUST00000177498 6.017±0.94 1.158±0.00 2.625±0.00 4.875±1.09 3.297±0.60 2.444±0.51 3.553±0.22 10.247±1.57 1.340±0.00 3.408±0.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P5 CIL_0008P5_0002 VISTA 3:88218217-88823366
CIL_000898 CIL_000898_0002 VISTA 3:88224783-88827970

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 IDA cell morphogenesis
GO:0005089 IDA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0007015 IPI actin filament organization
GO:0008017 IDA microtubule binding
GO:0032321 IEA:IDA positive regulation of Rho GTPase activity
GO:0035023 IDA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0043025 IDA neuronal cell body
GO:0043198 IDA dendritic shaft
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000313667 ARHGEF2-002 protein_coding Homo_sapiens 0 2872
ENST00000313695 ARHGEF2-003 protein_coding Homo_sapiens 0 2911
ENST00000361247 ARHGEF2-001 protein_coding Homo_sapiens 0 2926
ENST00000368315 ARHGEF2-201 protein_coding Homo_sapiens 0 1020
ENST00000462460 ARHGEF2-004 protein_coding Homo_sapiens 0 3007
ENST00000465079 ARHGEF2-011 retained_intron Homo_sapiens 0 213
ENST00000470874 ARHGEF2-009 nonsense_mediated_decay Homo_sapiens 0 398
ENST00000471589 ARHGEF2-010 protein_coding Homo_sapiens 0 869
ENST00000476273 ARHGEF2-008 processed_transcript Homo_sapiens 0 375
ENST00000487755 ARHGEF2-006 retained_intron Homo_sapiens 0 217
ENST00000495070 ARHGEF2-005 protein_coding Homo_sapiens 8.99998e-41 171
ENST00000497907 ARHGEF2-012 protein_coding Homo_sapiens 0 815
ENST00000608543 ARHGEF2-013 retained_intron Homo_sapiens 0 219
ENST00000609707 ARHGEF2-018 protein_coding Homo_sapiens 0 623

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