C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: vav 2 oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000185188 Vav2-002 ENSMUSG00000009621 10090 - 2:27262104-27426912 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENSMUST00000185188
Transcript ID Brain
ENSMUST00000185188 6.811±1.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014Y CIL_00014Y_0002 CGP 2:27188393-27427033
CIL_00014Z CIL_00014Z_0002 CGP 2:27262104-27507662

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IMP guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005154 IPI epidermal growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007264 IMP small GTPase mediated signal transduction
GO:0016477 IGI cell migration
GO:0030031 IGI cell projection assembly
GO:0030032 IGI lamellipodium assembly
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043547 IMP positive regulation of GTPase activity
GO:0043552 IGI positive regulation of phosphatidylinositol 3-kinase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000371850 VAV2-001 protein_coding Homo_sapiens 0 2270
ENST00000371851 VAV2-002 protein_coding Homo_sapiens 0 2093
ENST00000406606 VAV2-003 protein_coding Homo_sapiens 0 2093
ENST00000486113 VAV2-004 processed_transcript Homo_sapiens 0 303

Loading