C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: twinfilin, actin-binding protein, homolog 2 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000188650 Twf2-003 ENSMUSG00000023277 10090 + 9:106206798-106215387 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000188650
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000188650 3.476±1.02 17.854±7.00 15.629±9.38 5.604±0.75 80.465±20.47 5.207±2.28 1.022±0.31 8.870±1.28 73.570±8.97 7.541±2.49 8.868±4.74 2.047±0.87

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NT CIL_0008NT_0002 VISTA 9:106082995-106685663
CIL_00087C CIL_00087C_0002 VISTA 9:106116951-106718793

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003785 IDA actin monomer binding
GO:0005080 ISA protein kinase C binding
GO:0005524 ISA ATP binding
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 ISA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0030016 IDA myofibril
GO:0030027 IDA lamellipodium
GO:0030030 IEA cell projection organization
GO:0030175 IDA filopodium
GO:0030837 IDA negative regulation of actin filament polymerization
GO:0032420 IDA stereocilium
GO:0032532 IC regulation of microvillus length
GO:0035556 ISA intracellular signal transduction
GO:0042989 IDA sequestering of actin monomers
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051016 IDA barbed-end actin filament capping

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000305533 TWF2-001 protein_coding Homo_sapiens 0 1223
ENST00000472755 TWF2-002 retained_intron Homo_sapiens 0 553
ENST00000478201 TLR9-002 nonsense_mediated_decay Homo_sapiens 2e-38 163
ENST00000494383 TLR9-001 protein_coding Homo_sapiens 0 564
ENST00000499914 TWF2-005 protein_coding Homo_sapiens 0 824

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