C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, ATPase, 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000157812 PSMC4-001 ENSG00000013275 9606 + 19:39971005-39981441 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000157812
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000157812 6.889±0.00 3.877±0.00 13.455±0.00 5.003±0.00 3.564±0.51 5.123±3.47 19.958±0.00 9.470±0.00 3.122±0.00 5.698±2.84 31.326±22.03 33.371±9.00 30.969±10.48

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0001824 IEA blastocyst development
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006200 TAS ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006508 TAS proteolysis
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0009378 IEA four-way junction helicase activity
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016234 IEA inclusion body
GO:0016787 IEA hydrolase activity
GO:0016887 TAS:IEA ATPase activity
GO:0022624 ISS proteasome accessory complex
GO:0030163 IEA protein catabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031597 IEA cytosolic proteasome complex
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000032824 Psmc4-001 protein_coding Mus_musculus 0 1786
ENSMUST00000135482 Psmc4-002 retained_intron Mus_musculus 0 1694
ENSDART00000034078 psmc4-001 protein_coding Danio_rerio 0 1110
ENSMUST00000140053 Psmc4-005 processed_transcript Mus_musculus 0 830
ENSMUST00000126528 Psmc4-004 retained_intron Mus_musculus 0 675
ENSMUST00000134486 Psmc4-006 retained_intron Mus_musculus 0 623
ENSMUST00000138512 Psmc4-003 retained_intron Mus_musculus 0 484
ENSDART00000053834 psmc6-001 protein_coding Danio_rerio 8e-21 106
ENSDART00000152444 psmc6-002 nonsense_mediated_decay Danio_rerio 0.000000004 68

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