C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAP2A, member of RAS oncogene family
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000245304 RAP2A-001 ENSG00000125249 9606 + 13:97434222-97469128 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245304
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245304 0.647±0.00 1.507±0.00 9.678±0.00 4.172±0.00 1.857±0.00 1.800±0.00 1.661±0.00 2.726±1.17 4.140±0.00 1.872±0.99 3.129±1.95 3.162±3.48 2.123±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00041S CIL_00041S_0001 CGP 13:97221434-97469128
CIL_0000O3 CIL_0000O3_0001 CGP 13:97434222-98024297

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IDA:IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005829 IEA cytosol
GO:0006184 IEA GTP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006913 IEA nucleocytoplasmic transport
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0030336 IEA negative regulation of cell migration
GO:0031532 IDA actin cytoskeleton reorganization
GO:0031954 IDA positive regulation of protein autophosphorylation
GO:0032486 ISS Rap protein signal transduction
GO:0034613 IDA cellular protein localization
GO:0045184 IDA establishment of protein localization
GO:0046328 IDA regulation of JNK cascade
GO:0048814 IDA regulation of dendrite morphogenesis
GO:0055037 IDA recycling endosome
GO:0055038 IDA recycling endosome membrane
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000062117 Rap2a-201 protein_coding Mus_musculus 0 1317
ENSMUST00000156694 Rap2a-001 protein_coding Mus_musculus 0 680
ENSDART00000058877 rap2ab-001 protein_coding Danio_rerio 0 580
ENSDART00000109750 CABZ01067868.1-201 protein_coding Danio_rerio 0 553
ENSMUST00000066298 B430305J03Rik-201 protein_coding Mus_musculus 0 512
ENSMUST00000049064 Rap2b-201 protein_coding Mus_musculus 0 512
ENSDART00000058967 rap2b-201 protein_coding Danio_rerio 0 497
ENSMUST00000099091 Ankub1-001 protein_coding Mus_musculus 5e-23 115

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