C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WNK lysine deficient protein kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000246914 WNK4-001 ENSG00000126562 9606 + 17:42780678-42796936 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastKidneyOvaryENST00000246914
Transcript ID Breast Kidney Ovary
ENST00000246914 0.782±0.00 9.447±0.00 12.220±0.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004HC CIL_0004HC_0001 CGP 17:42773436-42796936
CIL_0005SA CIL_0005SA_0001 CGP 17:42780678-42798704

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 ISS:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005923 ISS tight junction
GO:0006468 ISS:IEA protein phosphorylation
GO:0006811 ISS ion transport
GO:0006821 IEA chloride transport
GO:0008104 IEA protein localization
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019869 IDA chloride channel inhibitor activity
GO:0035556 ISS intracellular signal transduction
GO:0050794 ISS regulation of cellular process
GO:0050801 IMP ion homeostasis
GO:0070294 IMP renal sodium ion absorption
GO:0072156 IMP distal tubule morphogenesis
GO:0090188 IEA negative regulation of pancreatic juice secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000103108 Wnk4-001 protein_coding Mus_musculus 0 3847
ENSMUST00000147741 Wnk4-004 nonsense_mediated_decay Mus_musculus 0 2473
ENSMUST00000139487 Wnk4-002 nonsense_mediated_decay Mus_musculus 0 1866
ENSMUST00000170056 Wnk4-003 nonsense_mediated_decay Mus_musculus 0 503
ENSMUST00000170372 Wnk4-005 protein_coding Mus_musculus 3e-29 135

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