C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000253506 NFATC1-001 ENSG00000131196 9606 + 18:79395856-79529325 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainMuscleOvaryPlacentaENST00000253506
Transcript ID Brain Muscle Ovary Placenta
ENST00000253506 0.511±0.00 3.900±0.00 0.914±0.00 0.835±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KF CIL_0008KF_0001 VISTA 18:78942193-79542977
CIL_0008IX CIL_0008IX_0001 VISTA 18:78950009-79550795
CIL_0008HP CIL_0008HP_0001 VISTA 18:78983189-79584144
CIL_000016 CIL_000016_0002 CGP 18:79069285-79529325

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000980 ISS RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001085 ISS RNA polymerase II transcription factor binding
GO:0001205 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005528 TAS FK506 binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0035556 IDA intracellular signal transduction
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045087 TAS innate immune response
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048273 ISS mitogen-activated protein kinase p38 binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000078049 Nfatc1-202 protein_coding Mus_musculus 0 2241
ENSMUST00000170905 Nfatc1-204 protein_coding Mus_musculus 0 2191
ENSMUST00000167977 Nfatc1-203 protein_coding Mus_musculus 0 2001
ENSMUST00000035800 Nfatc1-201 protein_coding Mus_musculus 0 1748

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