C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: telomeric repeat binding factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000254942 TERF2-001 ENSG00000132604 9606 - 16:69355561-69385988 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonMuscleOvaryPlacentaTestisENST00000254942
Transcript ID Brain Colon Muscle Ovary Placenta Testis
ENST00000254942 13.883±9.18 16.649±0.00 42.335±0.00 18.950±3.26 13.299±3.13 18.326±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004I8 CIL_0004I8_0001 CGP 16:69343248-69408571
CIL_0008KB CIL_0008KB_0001 VISTA 16:69347064-69947578
CIL_0007FT CIL_0007FT_0001 CGP 16:69355561-69466266

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000723 IMP:IEA telomere maintenance
GO:0000781 IDA:IEA chromosome, telomeric region
GO:0000783 IDA nuclear telomere cap complex
GO:0000784 IEA nuclear chromosome, telomeric region
GO:0001309 NAS age-dependent telomere shortening
GO:0001673 IEA male germ cell nucleus
GO:0001701 IEA in utero embryonic development
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003691 ISS double-stranded telomeric DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0007004 IC telomere maintenance via telomerase
GO:0007049 IEA cell cycle
GO:0008022 IPI protein C-terminus binding
GO:0010834 IMP telomere maintenance via telomere shortening
GO:0016233 IMP telomere capping
GO:0030870 IDA Mre11 complex
GO:0031627 IDA telomeric loop formation
GO:0031848 IMP protection from non-homologous end joining at telomere
GO:0032205 IDA negative regulation of telomere maintenance
GO:0032206 IEA positive regulation of telomere maintenance
GO:0032214 NAS negative regulation of telomere maintenance via semi-conservative replication
GO:0042162 IEA:IDA telomeric DNA binding
GO:0042803 IEA:IPI protein homodimerization activity
GO:0070198 IMP protein localization to chromosome, telomeric region
GO:0090398 NAS cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000133925 Terf2-001 protein_coding Mus_musculus 0 1847
ENSMUST00000068421 Terf2-201 protein_coding Mus_musculus 0 1838
ENSMUST00000116425 Terf2-002 protein_coding Mus_musculus 0 1491
ENSMUST00000068388 Terf2-003 protein_coding Mus_musculus 0 1258
ENSMUST00000142616 Terf2-004 nonsense_mediated_decay Mus_musculus 0 774
ENSMUST00000141205 Terf2-005 retained_intron Mus_musculus 0 409
ENSMUST00000136178 Terf2-006 retained_intron Mus_musculus 0 383

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