C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Kirsten rat sarcoma viral oncogene homolog
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000256078 KRAS-004 ENSG00000133703 9606 - 12:25209431-25250803 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryENST00000256078
Transcript ID Ovary
ENST00000256078 5.564±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004XD CIL_0004XD_0001 CGP 12:25108420-25209645
CIL_0006UC CIL_0006UC_0001 CGP 12:25195216-25250936
CIL_0004X7 CIL_0004X7_0001 CGP 12:25204789-25648579

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 TAS MAPK cascade
GO:0000186 TAS activation of MAPKK activity
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005739 IEA mitochondrion
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006184 IEA GTP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006913 IEA nucleocytoplasmic transport
GO:0007165 IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008542 IEA visual learning
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010628 IMP positive regulation of gene expression
GO:0015031 IEA protein transport
GO:0016020 IDA:IEA membrane
GO:0019002 IEA GMP binding
GO:0019003 IEA GDP binding
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0030036 IEA actin cytoskeleton organization
GO:0030275 IEA LRR domain binding
GO:0032228 IEA regulation of synaptic transmission, GABAergic
GO:0032403 IDA protein complex binding
GO:0035022 IEA positive regulation of Rac protein signal transduction
GO:0035176 IEA social behavior
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045087 TAS innate immune response
GO:0045121 IEA membrane raft
GO:0045596 IEA negative regulation of cell differentiation
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048169 IEA regulation of long-term neuronal synaptic plasticity
GO:0050900 TAS leukocyte migration
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0051146 IEA striated muscle cell differentiation
GO:0051384 IEA response to glucocorticoid
GO:0051385 IEA response to mineralocorticoid
GO:0060441 IEA epithelial tube branching involved in lung morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000111710 Kras-002 protein_coding Mus_musculus 0 1415
ENSMUST00000032399 Kras-001 protein_coding Mus_musculus 0 784
ENSMUST00000123972 Kras-005 processed_transcript Mus_musculus 0 440
ENSMUST00000156486 Kras-006 nonsense_mediated_decay Mus_musculus 0 427
ENSMUST00000149314 Kras-004 retained_intron Mus_musculus 0 381
ENSMUST00000155145 Kras-003 protein_coding Mus_musculus 2e-40 171

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