C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phospholipase D2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263088 PLD2-001 ENSG00000129219 9606 + 17:4807096-4823434 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungOvaryPlacentaTestisENST00000263088
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000263088 2.531±0.00 3.661±0.00 0.454±0.00 3.955±3.07 0.140±0.00 0.655±0.34 1.482±0.00 5.995±0.00 7.130±4.94 5.885±2.93 1.470±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001RF CIL_0001RF_0001 CGP 17:4796144-4823434
CIL_0001RG CIL_0001RG_0001 CGP 17:4807096-4898061

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002031 IEA G-protein coupled receptor internalization
GO:0003824 IEA catalytic activity
GO:0004630 IEA phospholipase D activity
GO:0005515 IPI protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 TAS plasma membrane
GO:0006644 TAS phospholipid metabolic process
GO:0006654 TAS phosphatidic acid biosynthetic process
GO:0006655 TAS phosphatidylglycerol biosynthetic process
GO:0006898 IEA receptor-mediated endocytosis
GO:0007010 TAS cytoskeleton organization
GO:0007264 TAS small GTPase mediated signal transduction
GO:0008152 IEA metabolic process
GO:0016042 IEA lipid catabolic process
GO:0031526 IEA brush border membrane
GO:0035091 IEA phosphatidylinositol binding
GO:0036465 TAS synaptic vesicle recycling
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0070290 IEA N-acylphosphatidylethanolamine-specific phospholipase D activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018429 Pld2-001 protein_coding Mus_musculus 0 3302
ENSMUST00000108557 Pld2-006 protein_coding Mus_musculus 0 2446
ENSMUST00000108556 Pld2-002 protein_coding Mus_musculus 0 1142
ENSMUST00000179806 Pld2-007 retained_intron Mus_musculus 0 606
ENSMUST00000146248 Pld2-004 retained_intron Mus_musculus 0 468

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