C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase D2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129219 PLD2 9606 + 17:4807096-4823434 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263088 PLD2-001 4807096-4823434 protein_coding
  ENST00000571273 PLD2-010 4817944-4819213 retained_intron
  ENST00000572127 PLD2-011 4818198-4819465 retained_intron
  ENST00000572199 PLD2-009 4816708-4817375 retained_intron
  ENST00000572940 PLD2-015 4807169-4823428 protein_coding
  ENST00000573258 PLD2-008 4815903-4817137 retained_intron
  ENST00000574268 PLD2-003 4807192-4809118 retained_intron
  ENST00000574796 PLD2-006 4814150-4815869 retained_intron
  ENST00000575246 PLD2-002 4807183-4818385 nonsense_mediated_decay
  ENST00000575316 PLD2-004 4807562-4809325 protein_coding
  ENST00000575813 PLD2-005 4810807-4815554 nonsense_mediated_decay
  ENST00000575945 PLD2-014 4821640-4822795 retained_intron
  ENST00000576329 PLD2-007 4815859-4816905 retained_intron
  ENST00000576864 PLD2-013 4818593-4823434 protein_coding
  ENST00000576983 PLD2-012 4817146-4819515 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263088ENST00000572940ENST00000574796ENST00000575246ENST00000575316ENST00000575813ENST00000576864ENST00000576983
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263088 2.531±0.00 3.661±0.00 N/A 0.454±0.00 3.955±3.07 0.140±0.00 0.655±0.34 1.482±0.00 N/A 5.995±0.00 N/A 7.130±4.94 5.885±2.93 1.470±0.00
ENST00000572940 6.590±0.00 8.502±0.00 0.558±0.00 2.822±2.51 N/A 2.689±0.00 0.566±0.00 1.265±0.99 0.350±0.00 N/A 0.983±0.00 7.004±2.59 4.710±1.46 2.257±1.64
ENST00000574796 N/A N/A N/A N/A N/A N/A 1.256±0.00 N/A 2.531±0.00 N/A N/A N/A N/A N/A
ENST00000575246 N/A N/A N/A 2.796±0.00 N/A N/A N/A N/A N/A N/A N/A 0.683±0.00 N/A N/A
ENST00000575316 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.012±0.00 N/A N/A N/A N/A
ENST00000575813 N/A N/A 1.879±0.00 N/A N/A N/A N/A 3.804±0.00 N/A N/A N/A N/A N/A N/A
ENST00000576864 N/A N/A 0.788±0.00 N/A N/A 2.796±0.00 N/A N/A N/A N/A N/A 24.456±0.00 15.795±0.00 5.185±1.51
ENST00000576983 N/A N/A N/A 1.723±0.00 N/A 3.000±0.00 N/A N/A N/A N/A N/A 28.430±0.00 26.063±0.00 5.057±1.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001RF CIL_0001RF_0001 CGP 17:4796144-4823434
CIL_0001RG CIL_0001RG_0001 CGP 17:4807096-4898061

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002031 IEA G-protein coupled receptor internalization
GO:0003824 IEA catalytic activity
GO:0004630 IEA phospholipase D activity
GO:0005515 IPI protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 TAS plasma membrane
GO:0006644 TAS phospholipid metabolic process
GO:0006654 TAS phosphatidic acid biosynthetic process
GO:0006655 TAS phosphatidylglycerol biosynthetic process
GO:0006898 IEA receptor-mediated endocytosis
GO:0007010 TAS cytoskeleton organization
GO:0007264 TAS small GTPase mediated signal transduction
GO:0008152 IEA metabolic process
GO:0016042 IEA lipid catabolic process
GO:0031526 IEA brush border membrane
GO:0035091 IEA phosphatidylinositol binding
GO:0036465 TAS synaptic vesicle recycling
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0070290 IEA N-acylphosphatidylethanolamine-specific phospholipase D activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034262 pld2 phospholipase D2 protein_coding Danio_rerio
ENSMUSG00000020828 Pld2 phospholipase D2 protein_coding Mus_musculus

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