C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cullin 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264414 CUL3-001 ENSG00000036257 9606 - 2:224470150-224585348 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000264414
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000264414 1.159±0.00 1.510±0.00 0.819±0.00 2.762±0.55 1.036±0.16 1.005±0.06 0.826±0.31 1.424±0.00 0.840±0.00 0.968±0.10 2.353±0.00 1.739±0.45 0.980±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XN CIL_0006XN_0001 CGP 2:224378698-224585397
CIL_0006XM CIL_0006XM_0001 CGP 2:224470150-225042445

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000139 IMP Golgi membrane
GO:0000209 IDA protein polyubiquitination
GO:0000902 IEA cell morphogenesis
GO:0001701 IEA in utero embryonic development
GO:0001831 IEA trophectodermal cellular morphogenesis
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005794 IEA Golgi apparatus
GO:0005827 IDA polar microtubule
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006513 IDA protein monoubiquitination
GO:0006888 IDA ER to Golgi vesicle-mediated transport
GO:0007050 TAS cell cycle arrest
GO:0007080 IMP mitotic metaphase plate congression
GO:0007229 ISS integrin-mediated signaling pathway
GO:0007369 IEA gastrulation
GO:0008054 IDA cyclin catabolic process
GO:0008284 TAS positive regulation of cell proliferation
GO:0016020 IDA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0016477 IMP cell migration
GO:0016567 IDA protein ubiquitination
GO:0017145 ISS stem cell division
GO:0030332 IEA cyclin binding
GO:0031208 IDA POZ domain binding
GO:0031461 IEA cullin-RING ubiquitin ligase complex
GO:0031463 IDA Cul3-RING ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032467 IMP positive regulation of cytokinesis
GO:0035024 IMP negative regulation of Rho protein signal transduction
GO:0040016 ISS embryonic cleavage
GO:0042803 IEA protein homodimerization activity
GO:0043149 IMP stress fiber assembly
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045842 IMP positive regulation of mitotic metaphase/anaphase transition
GO:0046982 IEA protein heterodimerization activity
GO:0048208 IMP COPII vesicle coating
GO:0070062 IDA extracellular vesicular exosome
GO:0097193 TAS intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000163119 Cul3-001 protein_coding Mus_musculus 0 5001
ENSMUST00000164108 Cul3-002 protein_coding Mus_musculus 0 3583
ENSMUST00000167794 Cul3-006 retained_intron Mus_musculus 0 771
ENSMUST00000170897 Cul3-003 nonsense_mediated_decay Mus_musculus 0 743
ENSMUST00000168372 Cul3-005 protein_coding Mus_musculus 0 538
ENSMUST00000167293 Cul3-004 nonsense_mediated_decay Mus_musculus 0 477
ENSDART00000125379 protein_coding Danio_rerio 7e-37 161

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