C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: thyroid hormone receptor, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264637 THRA-001 ENSG00000126351 9606 + 17:40062810-40093867 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverOvaryPlacentaTestisENST00000264637
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENST00000264637 9.080±0.00 4.490±0.00 1.183±0.00 32.071±26.92 10.735±0.00 27.027±0.00 6.672±0.00 1.359±0.42 35.289±1.42 7.169±0.00 18.131±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0001 VISTA 17:39768583-40372873
CIL_0002PX CIL_0002PX_0001 CGP 17:40015361-40061215
CIL_0002KL CIL_0002KL_0001 CGP 17:40019097-40093867
CIL_0002L8 CIL_0002L8_0001 CGP 17:40058290-40100725

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001502 IEA cartilage condensation
GO:0001503 IEA ossification
GO:0002153 IEA steroid receptor RNA activator RNA binding
GO:0002155 IEA regulation of thyroid hormone mediated signaling pathway
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003727 IEA single-stranded RNA binding
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004887 IEA:IDA thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007611 IEA learning or memory
GO:0008016 IEA regulation of heart contraction
GO:0008050 IEA female courtship behavior
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0009409 IEA response to cold
GO:0009755 IDA hormone-mediated signaling pathway
GO:0009887 IEA organ morphogenesis
GO:0010467 TAS gene expression
GO:0010831 IEA positive regulation of myotube differentiation
GO:0017025 IDA TBP-class protein binding
GO:0017055 IDA negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0019904 IPI protein domain specific binding
GO:0030218 IEA erythrocyte differentiation
GO:0030878 IEA thyroid gland development
GO:0031490 IEA chromatin DNA binding
GO:0032403 IEA protein complex binding
GO:0033032 IEA regulation of myeloid cell apoptotic process
GO:0042994 IEA cytoplasmic sequestering of transcription factor
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045925 IEA positive regulation of female receptivity
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050994 IEA regulation of lipid catabolic process
GO:0060509 IEA Type I pneumocyte differentiation
GO:0070324 IDA thyroid hormone binding
GO:2000143 IDA negative regulation of DNA-templated transcription, initiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000064187 Thra-001 protein_coding Mus_musculus 0 3415
ENSMUST00000103139 Thra-003 protein_coding Mus_musculus 0 2270
ENSMUST00000124072 Thra-004 protein_coding Mus_musculus 0 1781
ENSMUST00000152195 Thra-002 processed_transcript Mus_musculus 0 990
ENSDART00000000160 thraa-001 protein_coding Danio_rerio 0 761
ENSDART00000151127 thraa-002 protein_coding Danio_rerio 0 761
ENSMUST00000153043 Thra-007 protein_coding Mus_musculus 0 632
ENSMUST00000064941 Nr1d1-001 protein_coding Mus_musculus 0 486
ENSDART00000151575 thraa-003 retained_intron Danio_rerio 0 405
ENSMUST00000150693 Thra-006 processed_transcript Mus_musculus 0 394
ENSMUST00000153468 Thra-009 processed_transcript Mus_musculus 0 394
ENSMUST00000124130 Thra-008 processed_transcript Mus_musculus 2e-20 102

Loading