C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tumor protein p63
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264731 TP63-001 ENSG00000073282 9606 + 3:189631427-189897279 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastTestisENST00000264731
Transcript ID Breast Testis
ENST00000264731 0.446±0.00 1.046±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003Y5 CIL_0003Y5_0002 CGP 3:188947214-189897279
CIL_000933 CIL_000933_0001 VISTA 3:189215860-189816512
CIL_0000DP CIL_0000DP_0001 CGP 3:189631416-190122437

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IBA chromatin
GO:0000790 IDA nuclear chromatin
GO:0000989 IEA transcription factor binding transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001302 IEA replicative cell aging
GO:0001501 IEA skeletal system development
GO:0001736 IEA establishment of planar polarity
GO:0001738 IEA morphogenesis of a polarized epithelium
GO:0001942 IEA hair follicle development
GO:0002039 IBA p53 binding
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0002064 IEA epithelial cell development
GO:0003677 NAS DNA binding
GO:0003682 IBA chromatin binding
GO:0003684 IBA damaged DNA binding
GO:0003690 IBA double-stranded DNA binding
GO:0003700 IBA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005667 IBA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005791 IEA rough endoplasmic reticulum
GO:0005829 IBA cytosol
GO:0006338 IEA chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006915 TAS apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006978 IBA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007219 IEA Notch signaling pathway
GO:0007283 IEA spermatogenesis
GO:0007389 IEA pattern specification process
GO:0007499 IEA ectoderm and mesoderm interaction
GO:0007569 IEA cell aging
GO:0008544 IEA epidermis development
GO:0009887 IEA organ morphogenesis
GO:0009954 IEA proximal/distal pattern formation
GO:0010165 IBA response to X-ray
GO:0010259 IEA multicellular organismal aging
GO:0010332 IBA response to gamma radiation
GO:0010481 IEA epidermal cell division
GO:0010482 ISS regulation of epidermal cell division
GO:0010838 IEA positive regulation of keratinocyte proliferation
GO:0019904 IEA protein domain specific binding
GO:0030154 IEA cell differentiation
GO:0030216 IEA keratinocyte differentiation
GO:0030326 IEA embryonic limb morphogenesis
GO:0030425 IBA dendrite
GO:0030850 IEA prostate gland development
GO:0030855 IEA epithelial cell differentiation
GO:0030859 IEA polarized epithelial cell differentiation
GO:0031069 IEA hair follicle morphogenesis
GO:0031571 IBA mitotic G1 DNA damage checkpoint
GO:0034644 IBA cellular response to UV
GO:0036342 IEA post-anal tail morphogenesis
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042771 IBA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042802 IPI identical protein binding
GO:0043005 IEA neuron projection
GO:0043066 IEA negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0043281 IEA regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043523 IBA regulation of neuron apoptotic process
GO:0043565 IBA sequence-specific DNA binding
GO:0043589 IEA skin morphogenesis
GO:0043616 IEA keratinocyte proliferation
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045617 IEA negative regulation of keratinocyte differentiation
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0045747 IDA positive regulation of Notch signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048485 IEA sympathetic nervous system development
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0048745 IEA smooth muscle tissue development
GO:0048807 IEA female genitalia morphogenesis
GO:0050699 IPI WW domain binding
GO:0051262 IEA protein tetramerization
GO:0051289 IPI protein homotetramerization
GO:0051402 IEA neuron apoptotic process
GO:0060157 IEA urinary bladder development
GO:0060197 IEA cloacal septation
GO:0060513 IEA prostatic bud formation
GO:0060529 IEA squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0061436 ISS establishment of skin barrier
GO:1902808 IMP positive regulation of cell cycle G1/S phase transition
GO:2000271 IDA positive regulation of fibroblast apoptotic process
GO:2000381 IEA negative regulation of mesoderm development
GO:2000773 IMP negative regulation of cellular senescence
GO:2001235 IEA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115310 Trp63-003 protein_coding Mus_musculus 0 3269
ENSMUST00000040231 Trp63-001 protein_coding Mus_musculus 0 2741
ENSMUST00000115306 Trp63-002 protein_coding Mus_musculus 0 2663
ENSMUST00000065523 Trp63-201 protein_coding Mus_musculus 0 2340
ENSMUST00000115308 Trp63-202 protein_coding Mus_musculus 0 1847
ENSMUST00000115305 Trp63-006 protein_coding Mus_musculus 0 1397
ENSMUST00000115304 Trp63-005 protein_coding Mus_musculus 0 1134
ENSMUST00000115307 Trp63-004 protein_coding Mus_musculus 0 891

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