C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: paxillin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000267257 PXN-201 ENSG00000089159 9606 - 12:120210439-120265771 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLiverLungOvaryENST00000267257
Transcript ID Adrenal Brain Breast Colon Heart Liver Lung Ovary
ENST00000267257 8.367±0.00 0.220±0.00 5.831±0.00 2.019±0.00 2.005±1.58 1.930±0.00 23.531±0.00 10.069±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009CQ CIL_0009CQ_0001 VISTA 12:119991644-120595694

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001725 IDA stress fiber
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005875 TAS microtubule associated complex
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006928 IEA cellular component movement
GO:0006936 TAS muscle contraction
GO:0007010 IEA cytoskeleton organization
GO:0007155 NAS cell adhesion
GO:0007165 TAS signal transduction
GO:0007172 TAS signal complex assembly
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008013 IPI beta-catenin binding
GO:0008270 IEA zinc ion binding
GO:0008360 IEA regulation of cell shape
GO:0017166 IPI vinculin binding
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0030027 IDA lamellipodium
GO:0030032 IEA lamellipodium assembly
GO:0031252 IEA cell leading edge
GO:0032403 IEA protein complex binding
GO:0034329 TAS cell junction assembly
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0034614 IEP cellular response to reactive oxygen species
GO:0045860 IEA positive regulation of protein kinase activity
GO:0048041 IEA focal adhesion assembly
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0051435 IEA BH4 domain binding
GO:0060396 IDA growth hormone receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000125007 Pxn-004 processed_transcript Mus_musculus 0 1164
ENSMUST00000152156 Pxn-005 retained_intron Mus_musculus 0 1164
ENSMUST00000067268 Pxn-001 protein_coding Mus_musculus 0 1164
ENSMUST00000086523 Pxn-002 protein_coding Mus_musculus 0 1162
ENSMUST00000137716 Pxn-007 processed_transcript Mus_musculus 0 828
ENSMUST00000157050 Pxn-008 processed_transcript Mus_musculus 0 773
ENSDART00000123180 pxna-201 protein_coding Danio_rerio 0 684
ENSDART00000126598 pxna-202 protein_coding Danio_rerio 0 678
ENSDART00000085993 PXN (1 of 3)-201 protein_coding Danio_rerio 0 660
ENSMUST00000125054 Pxn-003 retained_intron Mus_musculus 0 654
ENSMUST00000153682 Pxn-009 processed_transcript Mus_musculus 0 412
ENSMUST00000138139 Pxn-012 retained_intron Mus_musculus 0 364
ENSMUST00000134198 Pxn-013 processed_transcript Mus_musculus 0 333
ENSMUST00000127345 Pxn-010 processed_transcript Mus_musculus 0 289
ENSMUST00000129897 Pxn-006 processed_transcript Mus_musculus 0 285

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