C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: paxillin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000086523 Pxn-002 ENSMUSG00000029528 10090 + 5:115506808-115554978 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonLungOvaryPlacentaTestisENSMUST00000086523
Transcript ID Adipose Adrenal Brain Breast Colon Lung Ovary Placenta Testis
ENSMUST00000086523 6.467±0.35 4.935±1.44 3.440±1.43 11.329±0.84 18.461±5.87 20.432±4.67 7.241±2.10 11.590±6.27 6.897±2.62

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZA CIL_0007ZA_0002 VISTA 5:114966986-115567561
CIL_0009CQ CIL_0009CQ_0002 VISTA 5:115188390-115791906

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0001725 IEA stress fiber
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006928 IMP cellular component movement
GO:0007010 IMP cytoskeleton organization
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007229 IMP integrin-mediated signaling pathway
GO:0008013 IEA beta-catenin binding
GO:0008270 IEA zinc ion binding
GO:0008360 IMP regulation of cell shape
GO:0017166 IEA vinculin binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0030027 IDA lamellipodium
GO:0030032 IDA lamellipodium assembly
GO:0030159 TAS receptor signaling complex scaffold activity
GO:0031252 IDA cell leading edge
GO:0032403 IEA protein complex binding
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0034614 IEA cellular response to reactive oxygen species
GO:0045860 IMP positive regulation of protein kinase activity
GO:0048041 IDA focal adhesion assembly
GO:0048754 IDA branching morphogenesis of an epithelial tube
GO:0051435 IPI BH4 domain binding
GO:0060396 IEA growth hormone receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000228307 PXN-001 protein_coding Homo_sapiens 0 2191
ENST00000267257 PXN-201 protein_coding Homo_sapiens 0 1162
ENST00000323871 PXN-005 retained_intron Homo_sapiens 0 1247
ENST00000424649 PXN-002 protein_coding Homo_sapiens 0 1162
ENST00000440827 PXN-011 processed_transcript Homo_sapiens 0 361
ENST00000458477 PXN-003 protein_coding Homo_sapiens 0 1162
ENST00000536957 PXN-004 protein_coding Homo_sapiens 0 2163
ENST00000538144 PXN-006 processed_transcript Homo_sapiens 0 1149
ENST00000540221 PXN-010 processed_transcript Homo_sapiens 0 276
ENST00000543331 PXN-009 protein_coding Homo_sapiens 0 536
ENST00000546532 PXN-013 protein_coding Homo_sapiens 0 521
ENST00000547746 PXN-018 processed_transcript Homo_sapiens 0 276
ENST00000547983 PXN-017 nonsense_mediated_decay Homo_sapiens 0 900
ENST00000548912 PXN-012 protein_coding Homo_sapiens 0 521
ENST00000550795 PXN-015 protein_coding Homo_sapiens 0 549
ENST00000551327 PXN-021 processed_transcript Homo_sapiens 0 573
ENST00000552550 PXN-014 protein_coding Homo_sapiens 0 512

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