C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transducer of ERBB2, 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000268957 TOB1-002 ENSG00000141232 9606 - 17:50862980-50867978 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonLiverMuscleOvaryPlacentaTestisENST00000268957
Transcript ID Bladder Brain Breast Colon Liver Muscle Ovary Placenta Testis
ENST00000268957 3.349±0.00 1.812±0.00 2.602±0.00 2.899±0.00 3.483±0.00 18.814±0.00 13.477±7.06 2.714±1.39 12.119±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KM CIL_0007KM_0001 UCNEbase 17:50750455-50862724
CIL_0004X3 CIL_0004X3_0003 CGP 17:50834650-50867978
CIL_0004X0 CIL_0004X0_0003 CGP 17:50862223-51120865

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0008285 IDA negative regulation of cell proliferation
GO:0009967 TAS positive regulation of signal transduction
GO:0017148 IDA negative regulation of translation
GO:0030014 IDA CCR4-NOT complex
GO:0030971 IDA receptor tyrosine kinase binding
GO:0060212 IDA negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0060213 IDA positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:1900153 IDA positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000041589 Tob1-001 protein_coding Mus_musculus 0 1411
ENSDART00000049240 tob1a-001 protein_coding Danio_rerio 0 425

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