C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: microtubule-actin crosslinking factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000289893 MACF1-005 ENSG00000127603 9606 + 1:39331138-39486987 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000289893
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000289893 2.883±0.00 3.555±0.00 3.342±0.00 3.842±0.00 7.181±0.00 2.274±0.00 6.660±0.00 3.348±0.00 7.138±0.00 10.867±3.72 1.010±0.20 3.585±0.00 2.063±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G7 CIL_0008G7_0001 VISTA 1:38483085-39084457
CIL_0007Q3 CIL_0007Q3_0001 VISTA 1:38525828-39126769
CIL_000990 CIL_000990_0001 VISTA 1:38863737-39466035

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 IDA actin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005856 NAS:IEA cytoskeleton
GO:0005874 IDA microtubule
GO:0005886 IDA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0007050 IEA cell cycle arrest
GO:0008017 IEA microtubule binding
GO:0010632 ISS regulation of epithelial cell migration
GO:0016055 IEA Wnt signaling pathway
GO:0016887 ISS ATPase activity
GO:0030177 ISS positive regulation of Wnt signaling pathway
GO:0032587 IDA ruffle membrane
GO:0032886 IMP regulation of microtubule-based process
GO:0042060 ISS wound healing
GO:0043001 IDA Golgi to plasma membrane protein transport
GO:0044822 IDA poly(A) RNA binding
GO:0051015 NAS actin filament binding
GO:0051893 ISS regulation of focal adhesion assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000106213 Macf1-004 protein_coding Mus_musculus 0 16130
ENSMUST00000151346 Macf1-009 protein_coding Mus_musculus 0 15290
ENSMUST00000097897 Macf1-202 protein_coding Mus_musculus 0 8564
ENSMUST00000082108 Macf1-001 protein_coding Mus_musculus 0 8564
ENSMUST00000084301 Macf1-201 protein_coding Mus_musculus 0 8560
ENSMUST00000106224 Macf1-013 protein_coding Mus_musculus 0 8556
ENSMUST00000106220 Macf1-203 protein_coding Mus_musculus 0 8510
ENSMUST00000134458 Macf1-008 protein_coding Mus_musculus 0 8508
ENSMUST00000154824 Macf1-002 protein_coding Mus_musculus 0 3297
ENSMUST00000149022 Macf1-010 protein_coding Mus_musculus 0 1725
ENSMUST00000123765 Macf1-003 protein_coding Mus_musculus 0 1725
ENSMUST00000140596 Macf1-011 protein_coding Mus_musculus 0 1428
ENSMUST00000125447 Macf1-012 processed_transcript Mus_musculus 0 1205
ENSMUST00000147030 Macf1-005 protein_coding Mus_musculus 0 935
ENSMUST00000147228 Macf1-007 protein_coding Mus_musculus 0 935
ENSDART00000054274 macf1-201 protein_coding Danio_rerio 6e-27 130
ENSDART00000146394 macf1-001 protein_coding Danio_rerio 6e-27 130
ENSDART00000092780 DST-201 protein_coding Danio_rerio 0.000000000002 82

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