C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MER proto-oncogene, tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000295408 MERTK-001 ENSG00000153208 9606 + 2:111898479-112029561 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartKidneyLiverLungTestisENST00000295408
Transcript ID Adipose Adrenal Brain Colon Heart Kidney Liver Lung Testis
ENST00000295408 0.560±0.00 0.735±0.00 0.850±0.20 0.372±0.00 0.737±0.00 1.365±0.00 0.786±0.00 0.283±0.00 2.197±0.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047R CIL_00047R_0001 CGP 2:111766271-112029561
CIL_00038G CIL_00038G_0002 CGP 2:111898479-112119318

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001750 IEA photoreceptor outer segment
GO:0001779 IEA natural killer cell differentiation
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006468 TAS:IEA protein phosphorylation
GO:0006909 IMP phagocytosis
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007283 IEA spermatogenesis
GO:0007596 TAS blood coagulation
GO:0016021 IEA integral component of membrane
GO:0016028 IDA rhabdomere
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030168 IEA platelet activation
GO:0032940 IEA secretion by cell
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0043277 IEA apoptotic cell clearance
GO:0043491 IEA protein kinase B signaling
GO:0050766 IDA positive regulation of phagocytosis
GO:0050900 TAS leukocyte migration
GO:0051250 IEA negative regulation of lymphocyte activation
GO:0060041 IEA retina development in camera-type eye
GO:0060068 IEA vagina development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000014505 Mertk-001 protein_coding Mus_musculus 0 2621
ENSMUST00000140221 Mertk-002 processed_transcript Mus_musculus 0 1530

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