C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: maternal embryonic leucine zipper kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000298048 MELK-001 ENSG00000165304 9606 + 9:36572862-36677682 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartKidneyOvaryPlacentaENST00000298048
Transcript ID Breast Heart Kidney Ovary Placenta
ENST00000298048 0.282±0.00 0.123±0.00 0.116±0.00 0.446±0.00 0.698±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006K5 CIL_0006K5_0001 CGP 9:36336396-36677683
CIL_0006K6 CIL_0006K6_0001 CGP 9:36572862-37034185

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005938 IDA cell cortex
GO:0006468 IEA protein phosphorylation
GO:0006915 IDA apoptotic process
GO:0008283 IDA cell proliferation
GO:0008289 IEA lipid binding
GO:0008631 IEA intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IDA:IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030097 ISS hemopoiesis
GO:0043065 ISS positive regulation of apoptotic process
GO:0046777 IDA protein autophosphorylation
GO:0061351 ISS neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000045607 Melk-001 protein_coding Mus_musculus 0 1945
ENSMUST00000137759 Melk-004 processed_transcript Mus_musculus 0 547
ENSMUST00000137703 Melk-002 protein_coding Mus_musculus 0 483
ENSMUST00000125708 Melk-003 protein_coding Mus_musculus 0 337

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