C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, ATPase, 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000298852 PSMC3-001 ENSG00000165916 9606 - 11:47418769-47426437 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000298852
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000298852 3.475±0.00 3.833±0.00 2.852±0.00 1.854±0.00 1.306±0.00 10.338±0.00 6.753±4.48 10.451±3.79 8.901±0.00 17.306±0.00 12.117±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0003713 TAS transcription coactivator activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006200 ISS ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0009378 IEA four-way junction helicase activity
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016787 IEA hydrolase activity
GO:0016887 ISS:IEA ATPase activity
GO:0022624 ISS proteasome accessory complex
GO:0030163 IEA protein catabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:2001141 TAS regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000067663 Psmc3-001 protein_coding Mus_musculus 0 1742
ENSMUST00000002171 Psmc3-009 protein_coding Mus_musculus 0 1580
ENSMUST00000111441 Psmc3-002 protein_coding Mus_musculus 0 1332
ENSMUST00000185715 Psmc3-010 protein_coding Mus_musculus 0 1245
ENSDART00000007913 psmc3-201 protein_coding Danio_rerio 0 1101
ENSMUST00000146506 Psmc3-007 nonsense_mediated_decay Mus_musculus 0 972
ENSMUST00000152269 Psmc3-005 processed_transcript Mus_musculus 0 549
ENSMUST00000141462 Psmc3-003 processed_transcript Mus_musculus 0 538
ENSMUST00000151419 Psmc3-006 processed_transcript Mus_musculus 0 532
ENSMUST00000131473 Psmc3-004 processed_transcript Mus_musculus 0 431
ENSMUST00000145317 Psmc3-008 processed_transcript Mus_musculus 1e-38 165

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