C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mutated in colorectal cancers
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000302475 MCC-001 ENSG00000171444 9606 - 5:113022099-113294949 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302475
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302475 3.222±0.00 0.486±0.00 0.486±0.00 1.232±0.30 1.157±0.23 1.305±0.00 2.721±0.30 1.559±0.00 2.540±1.55 1.060±0.35 0.386±0.27 5.200±4.66 1.886±1.33 1.103±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UM CIL_0004UM_0001 CGP 5:112976702-113488830

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004872 TAS receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007165 TAS signal transduction
GO:0010633 IMP negative regulation of epithelial cell migration
GO:0016055 IEA Wnt signaling pathway
GO:0042995 IEA cell projection
GO:0050680 IDA negative regulation of epithelial cell proliferation
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000164666 Mcc-202 protein_coding Mus_musculus 0 3193
ENSMUST00000089874 Mcc-201 protein_coding Mus_musculus 0 2957
ENSDART00000128214 MCC-201 protein_coding Danio_rerio 0 1125

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