C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: iron-sulfur cluster assembly enzyme
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000311893 ISCU-001 ENSG00000136003 9606 + 12:108562601-108569384 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000311893
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000311893 43.719±0.00 50.057±0.00 20.251±0.00 68.902±4.38 35.644±13.72 42.696±31.96 117.332±84.40 56.639±44.70 26.805±4.94 44.751±23.65 66.025±34.37 66.832±42.12 85.006±7.78 67.005±0.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001M7 CIL_0001M7_0001 CGP 12:108522580-108569384
CIL_0007IZ CIL_0007IZ_0002 CGP 12:108562582-108598320

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005506 TAS:IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005829 IDA cytosol
GO:0009399 TAS nitrogen fixation
GO:0016226 TAS:IEA iron-sulfur cluster assembly
GO:0032947 IDA protein complex scaffold
GO:0044281 TAS small molecule metabolic process
GO:0051536 IEA iron-sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026937 Iscu-001 protein_coding Mus_musculus 0 625
ENSMUST00000025669 Gm16437-201 processed_pseudogene Mus_musculus 0 568
ENSMUST00000112312 Iscu-003 protein_coding Mus_musculus 0 534
ENSMUST00000112311 Iscu-002 protein_coding Mus_musculus 0 534
ENSMUST00000134881 Iscu-005 nonsense_mediated_decay Mus_musculus 0 466
ENSMUST00000145592 Iscu-007 protein_coding Mus_musculus 0 387
ENSMUST00000123616 Iscu-004 nonsense_mediated_decay Mus_musculus 0 375
ENSMUST00000145778 Iscu-006 protein_coding Mus_musculus 6e-35 152

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