C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Kirsten rat sarcoma viral oncogene homolog
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000311936 KRAS-001 ENSG00000133703 9606 - 12:25204789-25250931 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000311936
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000311936 6.924±0.00 4.940±0.00 2.215±0.00 7.943±1.55 2.309±0.42 3.816±0.56 1.939±0.85 2.502±0.37 1.745±0.20 4.263±1.41 2.523±0.00 3.935±1.01 4.343±1.84 4.194±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004XD CIL_0004XD_0001 CGP 12:25108420-25209645
CIL_0006UC CIL_0006UC_0001 CGP 12:25195216-25250936
CIL_0004X7 CIL_0004X7_0001 CGP 12:25204789-25648579

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 TAS MAPK cascade
GO:0000186 TAS activation of MAPKK activity
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010628 IMP positive regulation of gene expression
GO:0015031 IEA protein transport
GO:0016020 IDA:IEA membrane
GO:0032403 IDA protein complex binding
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050900 TAS leukocyte migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000032399 Kras-001 protein_coding Mus_musculus 0 1310
ENSMUST00000111710 Kras-002 protein_coding Mus_musculus 0 850
ENSMUST00000156486 Kras-006 nonsense_mediated_decay Mus_musculus 0 647
ENSMUST00000123972 Kras-005 processed_transcript Mus_musculus 0 438
ENSMUST00000039729 Lyrm5-002 protein_coding Mus_musculus 0 339
ENSMUST00000155145 Kras-003 protein_coding Mus_musculus 1e-39 171

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