C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: malate dehydrogenase 2, NAD (mitochondrial)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000315758 MDH2-001 ENSG00000146701 9606 + 7:76048067-76067508 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000315758
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000315758 12.733±0.00 4.745±0.00 19.394±4.13 4.750±0.22 12.352±3.06 5.516±0.00 13.838±8.50 9.732±3.80 2.940±0.00 52.294±0.00 18.776±9.99 12.143±0.00 7.471±1.54

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NU CIL_0006NU_0001 CGP 7:75996338-76067508
CIL_0006NT CIL_0006NT_0001 CGP 7:76048051-76287288

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0005886 IDA plasma membrane
GO:0005975 TAS:IEA carbohydrate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006094 TAS gluconeogenesis
GO:0006099 TAS tricarboxylic acid cycle
GO:0006107 IEA oxaloacetate metabolic process
GO:0006108 IDA:IEA malate metabolic process
GO:0006475 IDA internal protein amino acid acetylation
GO:0006734 IEA NADH metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016615 IEA malate dehydrogenase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030060 IEA:IDA L-malate dehydrogenase activity
GO:0043621 IEA protein self-association
GO:0044237 TAS cellular metabolic process
GO:0044262 IEA cellular carbohydrate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0046554 IEA malate dehydrogenase (NADP+) activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000019323 Mdh2-001 protein_coding Mus_musculus 0 1088
ENSMUST00000138101 Mdh2-002 nonsense_mediated_decay Mus_musculus 0 791
ENSMUST00000121343 Gm12369-001 processed_pseudogene Mus_musculus 0 272

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