C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NIMA-related kinase 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000320246 NEK6-002 ENSG00000119408 9606 + 9:124257970-124353307 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000320246
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000320246 3.361±0.00 4.670±0.00 2.196±0.00 2.655±0.37 3.440±0.00 2.364±0.00 0.710±0.32 3.919±2.77 3.953±0.41 3.779±0.48 1.013±0.00 3.801±0.70 1.519±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MV CIL_0007MV_0001 UCNEbase 9:123742251-124385977
CIL_0008N3 CIL_0008N3_0001 VISTA 9:123985007-124587009
CIL_0006WH CIL_0006WH_0001 CGP 9:124001670-124353307
CIL_00098L CIL_00098L_0001 VISTA 9:124060941-124661966
CIL_0006WG CIL_0006WG_0001 CGP 9:124257606-124415444

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0000287 IDA magnesium ion binding
GO:0000910 TAS cytokinesis
GO:0004672 IEA protein kinase activity
GO:0004674 IEA:IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004871 IMP signal transducer activity
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005874 IEA microtubule
GO:0006468 IEA:IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007059 IDA chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0007077 TAS mitotic nuclear envelope disassembly
GO:0007165 IMP signal transduction
GO:0007346 TAS regulation of mitotic cell cycle
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0019894 IPI kinesin binding
GO:0019901 IPI protein kinase binding
GO:0030071 IDA regulation of mitotic metaphase/anaphase transition
GO:0031572 IMP G2 DNA damage checkpoint
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046777 IDA protein autophosphorylation
GO:0051225 TAS spindle assembly
GO:2000772 TAS regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000054234 Nek6-001 protein_coding Mus_musculus 0 1212
ENSMUST00000112895 Nek6-003 protein_coding Mus_musculus 0 1203
ENSMUST00000112902 Nek6-002 protein_coding Mus_musculus 0 1026
ENSMUST00000156726 Nek6-005 protein_coding Mus_musculus 0 438
ENSMUST00000151683 Nek6-004 protein_coding Mus_musculus 9.99967e-42 176

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